Sulfo-GMBS(N-γ-马来酰亚胺基丁酰-氧磺基琥珀酰亚胺酯)
Sulfo-GMBS(N-γ-马来酰亚胺基丁酰-氧磺基琥珀酰亚胺酯)
Thermo Scientific™

Sulfo-GMBS(N-γ-马来酰亚胺基丁酰-氧磺基琥珀酰亚胺酯)

Thermo Scientific Pierce Sulfo-GMBS 是一种水溶性胺-巯基交联剂,含有 NHS 酯和马来酰亚胺反应性基团,位于短间隔臂(7.3 埃)的相对两端了解更多信息
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货号数量
2232450 mg
货号 22324
价格(CNY)
4,944.00
Each
添加至购物车
数量:
50 mg
价格(CNY)
4,944.00
Each
添加至购物车
Thermo Scientific Pierce Sulfo-GMBS 是一种水溶性胺-巯基交联剂,含有 NHS 酯和马来酰亚胺反应性基团,位于短间隔臂(7.3 埃)的相对两端。

Sulfo-GMBS 的特点:

反应性基团sulfo-NHS 酯马来酰亚胺
可与以下基团发生反应:氨基和巯基
•不可裂解
•水溶性(与 GMBS 具有可比性)
•引发交联剂免疫应答的可能性较低,确保对抗原-载体蛋白偶联物的主要反应不会被对交联剂上的决定簇的反应所稀释
•据报告,GMBS 和 Sulfo-GMBS 的免疫原性低于 SMCC

产品参考:

交联剂应用指南 -- 检索本产品的最新参考文献

相关产品
GMBS(N-γ-马来酰亚胺基丁酰-氧琥珀酰亚胺酯)
仅供科研使用。不可用于诊断程序。
规格
细胞渗透性
描述Sulfo-GMBS
形式粉末
标记方法化学标记
分子量382.28
聚乙二醇化
产品线Pierce
数量50 mg
反应一部分马来酰亚胺、Sulfo-NHS 酯
运输条件环境
溶解度
间隔臂长7.3 Å
水溶性
化学反应性胺-巯基
可裂解
交联剂类型异型双功能团试剂
产品规格标准
产品类型交联剂
间隔子短 (<10 Å)
Unit SizeEach
内容与储存
接收后在 -20°C 下干燥储存。

常见问题解答 (FAQ)

Can you provide the shelf-life for Sulfo-GMBS (N-&gamma;-maleimidobutyryl-oxysulfosuccinimide ester)?

Sulfo-GMBS (N-γ-maleimidobutyryl-oxysulfosuccinimide ester) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.

引用和文献 (5)

引用和文献
Abstract
Solid phase DNA amplification: characterisation of primer attachment and amplification mechanisms.
Authors:Adessi C, Matton G, Ayala G, Turcatti G, Mermod JJ, Mayer P, Kawashima E
Journal:Nucleic Acids Res
PubMed ID:11024189
Different chemical methods used to attach oligonucleotides by their 5'-end on a glass surface were tested in the framework of solid phase PCR where surface-bound instead of freely-diffusing primers are used to amplify DNA. Each method was first evaluated for its capacity to provide a high surface coverage of oligonucleotides ... More
Ligand-receptor and receptor-receptor interactions act in concert to activate signaling in the Drosophila toll pathway.
Authors:Weber AN, Moncrieffe MC, Gangloff M, Imler JL, Gay NJ
Journal:J Biol Chem
PubMed ID:15795223
In Drosophila, the signaling pathway mediated by the Toll receptor is critical for the establishment of embryonic dorso-ventral pattern and for innate immune responses to bacterial and fungal pathogens. Toll is activated by high affinity binding of the cytokine Spätzle, a dimeric ligand of the cystine knot family. In vertebrates, ... More
Characterization of the oligomeric structure of the Ca(2+)-activated Cl- channel Ano1/TMEM16A.
Authors:Sheridan JT, Worthington EN, Yu K, Gabriel SE, Hartzell HC, Tarran R
Journal:J Biol Chem
PubMed ID:21056985
Members of the Anoctamin (Ano)/TMEM16A family have recently been identified as essential subunits of the Ca(2+)-activated chloride channel (CaCC). For example, Ano1 is highly expressed in multiple tissues including airway epithelia, where it acts as an apical conduit for transepithelial Cl(-) secretion and helps regulate lung liquid homeostasis and mucus ... More
Studying the protein organization of the postsynaptic density by a novel solid phase- and chemical cross-linking-based technology.
Authors:Liu SH, Cheng HH, Huang SY, Yiu PC, Chang YC
Journal:Mol Cell Proteomics
PubMed ID:16501281
Agarose beads carrying a cleavable, fluorescent, and photoreactive cross-linking reagent on the surface were synthesized and used to selectively pull out the proteins lining the surface of supramolecules. A quantitative comparison of the abundances of various proteins in the sample pulled out by the beads from supramolecules with their original ... More
Rat liver carnitine palmitoyltransferase 1 forms an oligomeric complex within the outer mitochondrial membrane.
Authors:Faye A, Esnous C, Price NT, Onfray MA, Girard J, Prip-Buus C
Journal:J Biol Chem
PubMed ID:17650509
Carnitine palmitoyltransferase (CPT) 1A catalyzes the rate-limiting step in the transport of long chain acyl-CoAs from cytoplasm to the mitochondrial matrix by converting them to acylcarnitines. Located within the outer mitochondrial membrane, CPT1A activity is inhibited by malonyl-CoA, its allosteric inhibitor. In this study, we investigate for the first time ... More