SMPH（琥珀酰亚胺 6-((β-马来酰亚胺丙酰氨基)己酸)）
SMPH（琥珀酰亚胺 6-((β-马来酰亚胺丙酰氨基)己酸)）
引用和文献 (2)
Thermo Scientific™

SMPH（琥珀酰亚胺 6-((β-马来酰亚胺丙酰氨基)己酸)）

Thermo Scientific Pierce SMPH 是一种胺对巯基交联剂，含有 NHS 酯和马来酰亚胺反应性基团，位于长间隔臂（14.2 埃）的相对两端了解更多信息
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货号数量
2236350 mg
货号 22363
价格（CNY)
4,700.00
Each
添加至购物车
数量:
50 mg
价格（CNY)
4,700.00
Each
添加至购物车
Thermo Scientific Pierce SMPH 是一种胺对巯基交联剂，含有 NHS 酯和马来酰亚胺反应性基团，位于长间隔臂（14.2 埃）的相对两端。

SMPH 的特点：

•反应性基团：NHS 酯和马来酰亚胺
•可与以下基团发生反应：氨基和巯基
•与 SMPB 相比，较长且溶解度较高
•NHS 酯在 pH 值 7-9 条件下与伯胺反应，形成稳定的酰胺键
•马来酰亚胺在 pH 值 6.5-7.5 条件下与 -SH 基团反应，形成稳定的硫醚键
•不可裂解
•不溶于水（首先溶于 DMF 或 DMSO）

产品参考：
交联剂应用指南 -- 检索本产品的最新参考文献

相关产品
SMPH（琥珀酰亚胺 6-((β-马来酰亚胺丙酰氨基)己酸)）
仅供科研使用。不可用于诊断程序。
规格
细胞渗透性是
描述SMPH
形式实心
标记方法化学标记
分子量379.36
聚乙二醇化否
产品线Pierce
数量50 mg
反应一部分马来酰亚胺、NHS 酯
运输条件环境
溶解度DMF、DMSO
间隔臂长14.2 Å
水溶性否
化学反应性胺-巯基
可裂解否
交联剂类型异型双功能团试剂
产品规格标准
产品类型交联剂
间隔子中等（10 至 30 Å）
Unit SizeEach
内容与储存
接收后，请在 4°C 下干燥储存。

常见问题解答 (FAQ)

Can you provide the shelf-life for SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))?

SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate)) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.

引用和文献 (2)

引用和文献
Abstract
Displaying Fel d1 on virus-like particles prevents reactogenicity despite greatly enhanced immunogenicity: a novel therapy for cat allergy.
Authors:Schmitz N, Dietmeier K, Bauer M, Maudrich M, Utzinger S, Muntwiler S, Saudan P, Bachmann MF
Journal:J Exp Med
PubMed ID:19667059
Allergen-specific desensitization is the only disease-modifying therapy currently available for the treatment of allergies. These therapies require application of allergen over several years and some may induce life-threatening anaphylactic reactions. An ideal vaccine for desensitization should be highly immunogenic and should alleviate allergic symptoms upon few injections while being nonreactogenic. ... More
Spatial and dynamic interactions between phospholamban and the canine cardiac Ca2+ pump revealed with use of heterobifunctional cross-linking agents.
Authors:Chen Z, Stokes DL, Rice WJ, Jones LR
Journal:J Biol Chem
PubMed ID:12972413
Heterobifunctional thiol to amine cross-linking agents were used to gain new insights on the dynamics and conformational factors governing the interaction between the cardiac Ca2+ pump (SERCA2a) and phospholamban (PLB). PLB is a small protein inhibitor of SERCA2a that reduces enzyme affinity for Ca2+ and thereby regulates cardiac contractility. We ... More