SMPB（琥珀酰亚胺基 4-(p-马来酰亚胺基苯基)丁酸酯）
SMPB（琥珀酰亚胺基 4-(p-马来酰亚胺基苯基)丁酸酯）
引用和文献 (4)
Thermo Scientific™

SMPB（琥珀酰亚胺基 4-(p-马来酰亚胺基苯基)丁酸酯）

Thermo Scientific Pierce SMPB 是一种胺对巯基交联剂，含有 NHS 酯和马来酰亚胺反应性基团（位于中等长度芳香族间隔臂（11.6 埃了解更多信息
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货号数量
2241650 mg
货号 22416
价格（CNY)
2,468.00
飞享价
Ends: 31-Dec-2025
3,150.00
共减 682.00 (22%)
Each
添加至购物车
数量:
50 mg
价格（CNY)
2,468.00
飞享价
Ends: 31-Dec-2025
3,150.00
共减 682.00 (22%)
Each
添加至购物车
Thermo Scientific Pierce SMPB 是一种胺对巯基交联剂，含有 NHS 酯和马来酰亚胺反应性基团（位于中等长度芳香族间隔臂（11.6 埃）的另一端）。

SMPB 的特点：

•反应性基团：NHS 酯和马来酰亚胺
•可与以下基团发生反应：氨基和巯基基团
• MBS 的扩展链类似物
• 不可裂解
• 不溶于水（首先溶于 DMF 或 DMSO）
•与 SMPB 形成的偶联物在血清中比 SPDP 偶联物更稳定

产品参考文献：
交联剂应用指南 -- 检索本产品的最新参考文献

相关产品
Sulfo-SMPB（磺基琥珀酰亚胺基 4-(N-马来酰亚胺基苯基)丁酸酯）
仅供科研使用。不可用于诊断程序。
规格
细胞渗透性是
描述SMPB
形式粉末
标记方法化学标记
分子量356.33
聚乙二醇化否
产品线Pierce
数量50 mg
反应一部分马来酰亚胺、NHS 酯
运输条件环境
溶解度DMF、DMSO
间隔臂长11.6 Å
水溶性否
化学反应性胺-巯基
可裂解否
交联剂类型异型双功能团试剂
产品规格标准
产品类型交联剂
间隔子中等（10 至 30 Å）
Unit SizeEach
内容与储存
接收后，请在 4°C 下干燥储存。

常见问题解答 (FAQ)

Can you provide the shelf-life for SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)?

SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.

引用和文献 (4)

引用和文献
Abstract
Covalent attachment of synthetic DNA to self-assembled monolayer films.
Authors:Chrisey LA, Lee GU, O'Ferrall CE
Journal:Nucleic Acids Res
PubMed ID:8760890
'The covalent attachment of thiol-modified DNA oligomers; to self-assembled monolayer silane films on fused silica and oxidized silicon substrates is described. A heterobifunctional crosslinking molecule bearing both thiol- and amino-reactive moieties was used to tether a DNA oligomer (modified at its terminus with a thiol group) to an aminosilane film ... More
Decorin is a novel antagonistic ligand of the Met receptor.
Authors:Goldoni S, Humphries A, Nyström A, Sattar S, Owens RT, McQuillan DJ, Ireton K, Iozzo RV
Journal:J Cell Biol
PubMed ID:19433454
'Decorin, a member of the small leucine-rich proteoglycan gene family, impedes tumor cell growth by down-regulating the epidermal growth factor receptor. Decorin has a complex binding repertoire, thus, we predicted that decorin would modulate the bioactivity of other tyrosine kinase receptors. We discovered that decorin binds directly and with high ... More
Dendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1 diabetes.
Authors:Karumuthil-Melethil S, Perez N, Li R, Prabhakar BS, Holterman MJ, Vasu C
Journal:J Immunol
PubMed ID:20483724
The levels of expression of alternatively spliced variants of CTLA-4 and insufficient CTLA-4 signaling have been implicated in type 1 diabetes. Hence, we hypothesized that increasing CTLA-4-specific ligand strength on autoantigen-presenting dendritic cells (DCs) can enhance ligation of CTLA-4 on T cells and lead to modulation of autoreactive T cell ... More
Visualizing dynamic cytoplasmic forces with a compliance-matched FRET sensor.
Authors:Meng F, Sachs F
Journal:J Cell Sci
PubMed ID:21172803
Mechanical forces are ubiquitous modulators of cell activity but little is known about the mechanical stresses in the cell. Genetically encoded FRET-based force sensors now allow the measurement of local stress in specific host proteins in vivo in real time. For a minimally invasive probe, we designed one with a ... More