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引用和文献 (7)
Thermo Scientific™
Halt™ 蛋白酶和磷酸酶抑制剂混合物 (100X)
Thermo Scientific Halt Protease and Phosphatase Inhibitor Cocktail (100X) provides the convenience of a single solution with full protein sample了解更多信息
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| 货号 | 数量 |
|---|---|
| 78442 | 24 x 100μL |
| 78446 | 10 mL |
| 78440 | 1 mL |
| 78444 | 5 x 1 mL |
货号 78442
价格（CNY)
3,074.00
飞享价
Ends: 27-Dec-2025
4,800.00共减 1,726.00 (36%)
Each
数量:
24 x 100μL
价格（CNY)
3,074.00
飞享价
Ends: 27-Dec-2025
4,800.00共减 1,726.00 (36%)
Each
Thermo Scientific Halt Protease and Phosphatase Inhibitor Cocktail (100X) provides the convenience of a single solution with full protein sample protection for cell and tissue lysates.
Features of Halt Protease and Phosphatase Inhibitor Cocktail (100X):
• Complete protection—all-in-one cocktail contains both protease and phosphatase inhibitors
• Multiple package sizes—choose from four convenient packages sizes to match nearly any scale
• Convenient —the 100X liquid formulation is much easier and more effective to use than individual inhibitors and other formats
• Easy storage—aqueous-based format allows for convenient cold-room storage without freezing, by contrast with DMSO-based cocktails
• Compatible—can be used in mass spectrometry (MS) because it does not contain AEBSF, which can cause peaks to shift
• Validated—fully compatible with Thermo Scientific Pierce Cell Lysis Buffers
Halt Protease and Phosphatase Inhibitor Cocktail is specifically optimized to protect proteins from degradation during extraction and purification. The cocktail contains inhibitors against the major classes of proteases and phosphatases, targeting aminopeptidases, cysteine and serine proteases and serine/threonine and protein tyrosine phosphatases. To promote the inhibition of metalloproteases, 0.5M EDTA is provided in a separate tube.
Related Products
Halt™ Protease and Phosphatase Inhibitor Cocktail, EDTA-free (100X)
Features of Halt Protease and Phosphatase Inhibitor Cocktail (100X):
• Complete protection—all-in-one cocktail contains both protease and phosphatase inhibitors
• Multiple package sizes—choose from four convenient packages sizes to match nearly any scale
• Convenient —the 100X liquid formulation is much easier and more effective to use than individual inhibitors and other formats
• Easy storage—aqueous-based format allows for convenient cold-room storage without freezing, by contrast with DMSO-based cocktails
• Compatible—can be used in mass spectrometry (MS) because it does not contain AEBSF, which can cause peaks to shift
• Validated—fully compatible with Thermo Scientific Pierce Cell Lysis Buffers
Halt Protease and Phosphatase Inhibitor Cocktail is specifically optimized to protect proteins from degradation during extraction and purification. The cocktail contains inhibitors against the major classes of proteases and phosphatases, targeting aminopeptidases, cysteine and serine proteases and serine/threonine and protein tyrosine phosphatases. To promote the inhibition of metalloproteases, 0.5M EDTA is provided in a separate tube.
Related Products
Halt™ Protease and Phosphatase Inhibitor Cocktail, EDTA-free (100X)
仅供科研使用。不可用于诊断程序。
规格
缓冲液裂解缓冲液
抑制剂蛋白酶抑制剂、磷酸酶抑制剂
数量24 x 100μL
试剂类型蛋白酶抑制剂、磷酸酶抑制剂
形式液体
产品线Halt
产品类型抑制剂混合物
Unit SizeEach
内容与储存
接收后，在 4°C 下储存
常见问题解答 (FAQ)
Can I store the 1X solution of the Halt Protease and Phosphatase Inhbitor Cocktail and if so, for how long?
What are the concentrations of the various components of the combined Halt Protease and Phosphatase Inhibitor Cocktail?
Do you offer the components of the Halt Protease and Phosphatase Cocktail individually?
When do I need to add EDTA when using the Halt Protease and Phosphatase Cocktail?
How much of the Halt Protease and Phosphatase Cocktail do I use for my sample?
引用和文献 (7)
引用和文献
Abstract
Sex-dependent effect of sublethal copper concentrations on de novo cholesterol synthesis in astrocytes and their possible links to variations in cholesterol and amyloid precursor protein levels in neuronal membranes.
Journal:Biology of sex differences
PubMed ID:38191520
BACKGROUND: Cholesterol (Cho) is an essential lipophilic molecule in cells; however, both its decrease and its increase may favor the development of neurological diseases such as Alzheimer's disease (AD). Although copper (Cu) is an essential trace metal for cells, the increased plasma concentration of its free form has been linked
Imlunestrant Is an Oral, Brain-Penetrant Selective Estrogen Receptor Degrader with Potent Antitumor Activity in ESR1 Wild-Type and Mutant Breast Cancer.
Journal:Cancer research
PubMed ID:39652577
Targeting of the estrogen receptor (ER) by antiestrogens is the standard of care for patients with ER+ HER2- advanced/metastatic breast cancer. Although antiestrogens that degrade ERα (fulvestrant) or block estrogen production (aromatase inhibitors) have improved patient outcomes, clinically important challenges remain related to drug administration, limited bioavailability, lack of brain
A PRMT5-ZNF326 axis mediates innate immune activation upon replication stress.
Journal:Science advances
PubMed ID:38838142
DNA replication stress (RS) is a widespread phenomenon in carcinogenesis, causing genomic instability and extensive chromatin alterations. DNA damage leads to activation of innate immune signaling, but little is known about transcriptional regulators mediating such signaling upon RS. Using a chemical screen, we identified protein arginine methyltransferase 5 (PRMT5) as
hCLCA1 and mCLCA3 are secreted non-integral membrane proteins and therefore are not ion channels.
Journal:J Biol Chem
PubMed ID:15919655
'Proteins of the CLCA gene family have been proposed to mediate calcium-activated chloride currents. In this study, we used detailed bioinformatics analysis and found that no transmembrane domains are predicted in hCLCA1 or mCLCA3 (Gob-5). Further analysis suggested that they are globular proteins containing domains that are likely to be
Quantitative PCR analysis of DNA, RNAs, and proteins in the same single cell.
Journal:Clin Chem
PubMed ID:23014600
The single cell represents the basic unit of all organisms. Most investigations have been performed on large cell populations, but understanding cell dynamics and heterogeneity requires single-cell analysis. Current methods for single-cell analysis generally can detect only one class of analytes.