BODIPY™ FL ATP-γ-S,硫酯(腺苷 5'-O-(3-硫代三磷酸),BODIPY™ FL 硫酯,钠盐)
BODIPY&trade; FL ATP-&gamma;-S,硫酯(腺苷 5'-<i>O</i>-(3-硫代三磷酸),BODIPY&trade; FL 硫酯,钠盐)
Invitrogen™

BODIPY™ FL ATP-γ-S,硫酯(腺苷 5'-O-(3-硫代三磷酸),BODIPY™ FL 硫酯,钠盐)

BODIPY™ FL ATP-γ-S 可以与 ATP 结合蛋白结合。这种荧光核苷酸是 BODIPY FL 荧光基团通过了解更多信息
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货号数量
A2218450 µL
货号 A22184
价格(CNY)
6,649.00
Each
添加至购物车
数量:
50 µL
价格(CNY)
6,649.00
Each
添加至购物车
BODIPY™ FL ATP-γ-S 可以与 ATP 结合蛋白结合。这种荧光核苷酸是 BODIPY FL 荧光基团通过 ATP-γ-S 的 γ-硫醇连接形成的。除了在结合研究方面的潜在用途之外,BODIPY FL ATP-γ-S 硫醚还是三联组氨酸核苷酸结合蛋白超家族成员 FHIT 的一种重要新底物。
仅供科研使用。不可用于诊断程序。
规格
标签或染料BODIPY™ FL
产品类型FL ATP-γ-S 硫酯
数量50 µL
运输条件湿冰
最大浓度5 mM
产品线BODIPY
Unit SizeEach
内容与储存
在冷冻冰箱(-5°C 至 -30°C)中避光储存。

引用和文献 (4)

引用和文献
Abstract
Fhit-nucleotide specificity probed with novel fluorescent and fluorogenic substrates.
Authors:Draganescu A, Hodawadekar SC, Gee KR, Brenner C
Journal:J Biol Chem
PubMed ID:10671479
'Fhit, a member of the histidine triad superfamily of nucleotide-binding proteins, binds and cleaves diadenosine polyphosphates and functions as a tumor suppressor in human epithelial cancers. Function of Fhit in tumor suppression does not require diadenosine polyphosphate cleavage but correlates with the ability to form substrate complexes. As diadenosine polyphosphates ... More
Spontaneous nucleotide exchange in low molecular weight GTPases by fluorescently labeled gamma-phosphate-linked GTP analogs.
Authors:Korlach J, Baird DW, Heikal AA, Gee KR, Hoffman GR, Webb WW
Journal:Proc Natl Acad Sci U S A
PubMed ID:14973186
Regulated guanosine nucleotide exchange and hydrolysis constitute the fundamental activities of low molecular weight GTPases. We show that three guanosine 5'-triphosphate analogs with BODIPY fluorophores coupled via the gamma phosphate bind to the GTPases Cdc42, Rac1, RhoA, and Ras and displace guanosine 5'-diphosphate with high intrinsic exchange rates in the ... More
Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers.
Authors:Pace HC, Hodawadekar SC, Draganescu A, Huang J, Bieganowski P, Pekarsky Y, Croce CM, Brenner C
Journal:Curr Biol
PubMed ID:10959838
BACKGROUND: The nucleotide-binding protein Fhit, among the earliest and most frequently inactivated proteins in lung cancer, suppresses tumor formation by inducing apoptosis. In invertebrates, Fhit is encoded as a fusion protein with Nit, a member of the nitrilase superfamily. In mice, the Nit1 and Fhit genes have nearly identical expression ... More
Exploration of the Effects of γ-Phosphate-Modified ATP Analogues on Histidine Kinase Autophosphorylation.
Authors:
Journal:Biochemistry
PubMed ID:29944360