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引用和文献 (12)
Invitrogen™
生物素叠氮化物（PEG4 羧酰胺-6-叠氮基己基生物素）
半抗原（生物素叠氮化物）通过铜催化点击反应与末端炔烃发生反应。随后可通过链霉素亲和素、亲和素或中性抗生物素蛋白®生物素结合蛋白检测生物素。了解更多信息
| 货号 | 数量 |
|---|---|
| B10184 | 1 mg |
货号 B10184
价格（CNY)
7,361.00
Each
数量:
1 mg
价格（CNY)
7,361.00
Each
半抗原（生物素叠氮化物）通过铜催化点击反应与末端炔烃发生反应。随后可通过链霉素亲和素、亲和素或中性抗生物素蛋白®生物素结合蛋白检测生物素。
仅供科研使用。不可用于诊断程序。
规格
化学反应性炔烃
产品规格实心
标签或染料生物素
分子量615.79 Da
产品类型生物素叠氮化物
数量1 mg
反应基团叠氮化物
反应一部分胺、叠氮化物
运输条件室温
溶解度DMSO (二甲亚砜)
颜色生物素
标签类型生物素和其他半抗原
产品线Molecular Probes
Unit SizeEach
内容与储存
在 ≤-20°C 下储存，并保持干燥。
引用和文献 (12)
引用和文献
Abstract
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination.
Journal:Proc Natl Acad Sci U S A
PubMed ID:20018730
'To initiate class switch recombination (CSR) activation-induced cytidine deaminase (AID) induces staggered nick cleavage in the S region, which lies 5'' to each Ig constant region gene and is rich in palindromic sequences. Topoisomerase 1 (Top1) controls the supercoiling of DNA by nicking, rotating, and religating one strand of DNA.
Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives.
Journal:Chem Res Toxicol
PubMed ID:18232660
'Polyunsaturated fatty acids (PUFA) are primary targets of free radical damage during oxidative stress. Diffusible electrophilic alpha,beta-unsaturated aldehydes, such as 4-hydroxynonenal (HNE), have been shown to modify proteins that mediate cell signaling (e.g., IKK and Keap1) and alter gene expression pathways responsible for inducing antioxidant genes, heat shock proteins, and
A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.
Journal:
PubMed ID:24589582
'Accumulating evidence suggests that dormant DNA replication origins play an important role in the recovery of stalled forks. However, their functional interactions with other fork recovery mechanisms have not been tested. We previously reported intrinsic activation of the Fanconi anemia (FA) pathway in a tumor-prone mouse model (Mcm4(chaos3)) with a
Metabolic labeling of sialic acids in living animals with alkynyl sugars.
Journal:Angew Chem Int Ed Engl
PubMed ID:19388017
Sialome sweet sialome: As sialic acids are involved in many host-pathogen recognition events and are markers of embryonic and malignant tissues, there is great interest in methods for the enrichment and identification of sialylated glycoproteins from complex tissues. Now N-(4-pentynoyl)mannosamine can be used to metabolically label sialylated glycoproteins in living
Regulation of the Skeletal Muscle Ryanodine Receptor/Ca2+-release Channel RyR1 by S-Palmitoylation.
Journal:
PubMed ID:24509862
The ryanodine receptor/Ca(2+)-release channels (RyRs) of skeletal and cardiac muscle are essential for Ca(2+) release from the sarcoplasmic reticulum that mediates excitation-contraction coupling. It has been shown that RyR activity is regulated by dynamic post-translational modifications of Cys residues, in particular S-nitrosylation and S-oxidation. Here we show that the predominant