Ion AmpliSeq™ Polyploidy Panel Kit with Ion GX5™ Chips (384 Samples)
Ion AmpliSeq™ Polyploidy Panel Kit with Ion GX5™ Chips (384 Samples)
Ion Torrent™

Ion AmpliSeq™ Polyploidy Panel Kit with Ion GX5™ Chips (384 Samples)

The Genexus System-compatible Ion AmpliSeq Polyploidy Panel Kit empowers accurate quality controls in preimplantation genetic testing for aneuploidy (PGT-A) by了解更多信息
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货号数量
GX55689384 samples
货号 GX55689
价格(CNY)
178,087.00
Each
添加至购物车
数量:
384 samples
价格(CNY)
178,087.00
Each
添加至购物车

The Genexus System-compatible Ion AmpliSeq Polyploidy Panel Kit empowers accurate quality controls in preimplantation genetic testing for aneuploidy (PGT-A) by leveraging SNP-based assessments.

Benefits of the Ion AmpliSeq Polyploidy Panel Kit include:
Germline SNP detection from embryo biopsy samples—no parental DNA required, enabling the extraction of genetic insights directly from the sample
Comprehensive genetic coverage—comprises 74 microhaplotype amplicons for human identification and 368 single SNP amplicons representing the population at large. With a total of 590 SNP sites covered, the panel unveils the unique genomic variations present in each sample, facilitating premium PGT-A analysis.
Triploidy 69,XXX identification—through the utilization of tri-allelic microhaplotype sites and allele frequency distributions, samples with the potentially lethal triploidy 69,XXX can be confidently identified. This abnormality often appears similar to the normal 46,XX on conventional PGT-A plots, but the panel's advanced techniques help overcome this challenge.
Mitigation of maternal contamination risk—reliable assessment of contamination from cumulus cell DNA made possible by tri-allelic microhaplotype sites. This assessment assists in prioritizing low-risk samples with minimized maternal contamination concerns.
Sibling embryo tracking—SNP clustering allows for the identification of genetically related embryos, helping prevent sample mix-ups. This functionality ensures that the most suitable embryos progress accordingly in the reproductive journey, optimizing the selection process.

Enhance sample prioritization in PGT-A through the implementation of SNP-based quality controls
Single nucleotide polymorphisms (SNPs) are unique genetic variations that can be inherited and directly associated with parental DNA. By leveraging SNPs, PGT-A analysis gains valuable insights into triploidy 69,XXX, maternal contamination, helping ease the selection of embryos for IVF reseach.

Notes
• This kit is compatible with the Genexus System.
 


仅供研究使用。
规格
数量384 samples
产品规格试剂盒
测序类型新一代测序
Unit SizeEach
内容与储存
• Ion AmpliSeq Polyploidy Panel, –10 to –30°C
• Ion AmpliSeq Lib Kit Plus, –10 to –30°C
• Genexus Cartridge, –10 to –30°C
• Genexus Bottle 2, 15–30°C
• Genexus Bottle 1 and 3, 15–30°C
• Genexus Strip 3-GX5, 2–8°C
• Genexus Strip 4, –10 to –30°C
• Genexus Coupler and GX5 Chip, 15–30°C

常见问题解答 (FAQ)

How should I store the Ion AmpliSeq Polyploidy Panel?

Ion AmpliSeq Polyploidy Panel should be stored at -10 to -30 degrees C.

Find additional tips, troubleshooting help, and resources within our Next-Generation Sequencing Support Center.

What version of software is compatible with the Ion AmpliSeq Polyploidy Panel on the Genexus instrument?

The Ion AmpliSeq Polyploidy Panel plugin requires Genexus Software v6.8 or later.

Find additional tips, troubleshooting help, and resources within our Next-Generation Sequencing Support Center.

Using the Ion AmpliSeq Polyploidy Panel, how many samples can be multiplexed on Ion 520 and 530 chips?

With the Ion 530 chip, you can run up to 60 samples per chip
With the Ion 520 chip, you can run up to 20 samples per chip

Find additional tips, troubleshooting help, and resources within our Next-Generation Sequencing Support Center.

How many samples can be run using the Ion AmpliSeq Polyploidy Panel?

The Ion AmpliSeq Polyploidy Panel is a single pool design for germline SNP detection and supplies sufficient reagents for running up to 96 samples.

Find additional tips, troubleshooting help, and resources within our Next-Generation Sequencing Support Center.

How much of each sample is needed for the Ion AmpliSeq Polyploidy Panel?

We recommend using at least 3 cells from embryo biopsy samples, keeping in mind that data quality increases with input. We have tested up to 10 cells in house but expect good tolerance at higher levels. If using gDNA, we recommend using at least 75 pg. Please note that dilutions of gDNA are prone to loss to plastics.

Find additional tips, troubleshooting help, and resources within our Next-Generation Sequencing Support Center.