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埃布硒仑
CAS: 60940-34-3 | C13H9NOSe | 274.192 g/mol
| 货号 | 数量 |
|---|---|
| J63190.MA 又称 J63190-MA | 10 mg |
化学标识符
CAS60940-34-3
IUPAC Name2-phenyl-2,3-dihydro-1,2-benzoselenazol-3-one
Molecular FormulaC13H9NOSe
InChI KeyDYEFUKCXAQOFHX-UHFFFAOYSA-N
SMILESO=C1N([Se]C2=CC=CC=C12)C1=CC=CC=C1
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规格
规格表
规格表FormCrystals or powder or crystalline powder
Appearance (Color)White to yellow to green
Melting Point (clear melt)179-184°C
Assay from Supplier's CofA≥97.5%
Ebselen inhibits 5-LO, CO, NADPH oxidize, and protein kinase C. It is a potent antioxidant. It possesses a unique glutathione peroxidase-like activity. It is also shown to be an inhibitor of free radical induced apoptosis and neuroprotective agent.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Ebselen inhibits 5-LO, CO, NADPH oxidize, and protein kinase C. It is a potent antioxidant. It possesses a unique glutathione peroxidase-like activity. It is also shown to be an inhibitor of free radical induced apoptosis and neuroprotective agent.
Solubility
Soluble in ethanol, methanol, acetone, acetonitrile.
Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
Ebselen inhibits 5-LO, CO, NADPH oxidize, and protein kinase C. It is a potent antioxidant. It possesses a unique glutathione peroxidase-like activity. It is also shown to be an inhibitor of free radical induced apoptosis and neuroprotective agent.
Solubility
Soluble in ethanol, methanol, acetone, acetonitrile.
Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only
General References:
- Helmut Sies. Ebselen, a selenoorganic compound as glutathione peroxidase mimic. Free Radical Biology and Medicine. 1993, 14,(3), 313-323.
- Tankred Schewe. Molecular actions of Ebselen—an anti-inflammatory antioxidant. General Pharmacology: The Vascular System. 1995, 26,(6), 1153-1169.