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Thermo Scientific Chemicals
Artemisinin, 98%
CAS: 63968-64-9 | C15H22O5 | 282.336 g/mol
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化学标识符
CAS63968-64-9
IUPAC Name(1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0⁴,¹³.0⁸,¹³]hexadecan-10-one
Molecular FormulaC15H22O5
InChI KeyBLUAFEHZUWYNDE-NNWCWBAJSA-N
SMILESC[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4
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规格
规格表
规格表FormCrystals or crystalline powder
Optical Rotation+70.0 to +80.0°
Appearance (Color)White
Infrared spectrumConforms
Assay from Supplier's CofA≥97.5% (HPLC)
Artemisinin inhibits angiogenesis by down-regulating HIF-1α and VEGF expression in mouse embryonic stem cells. Artemisinin crosses the blood-brain barrier and is an inhibitor of human NOS2 (iNOS).
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble to 100mM in DMSO and to 75mM in ethanol
Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat. Store in refrigerator.
Soluble to 100mM in DMSO and to 75mM in ethanol
Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat. Store in refrigerator.
RUO – Research Use Only
General References:
- Jurg Utzinger; Shu-Hua Xiao; Marcel Tanner; Jennifer Keiser. Artemisinins for schistosomiasis and beyond. Current Opinion in Investigational Drugs. 2007, 8, (2), 105-116.
- Rita Piedade; José Pedro Gil. The pharmacogenetics of antimalaria artemisinin combination therapy. Expert Opinion on Drug Metabolism and Toxicology. 2011, 7, (10), 1185-1200.