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引用和文献 (336)
Invitrogen™
红海海绵素 A
在亚微摩浓度的1:1复合物中，红海海绵素 A 能够结合单体 G-actin 肌动蛋白，破坏培养细胞中的微丝组织。其生理效应包括抑制受精、早期胚胎发育和免疫复合物吞噬内化。了解更多信息
| 货号 | 数量 |
|---|---|
| L12370 | 100 μg |
货号 L12370
价格（CNY)
6,472.00
飞享价
Ends: 31-Dec-2025
8,774.00共减 2,302.00 (26%)
Each
数量:
100 μg
价格（CNY)
6,472.00
飞享价
Ends: 31-Dec-2025
8,774.00共减 2,302.00 (26%)
Each
在亚微摩浓度的1:1复合物中，红海海绵素 A 能够结合单体 G-actin 肌动蛋白，破坏培养细胞中的微丝组织。其生理效应包括抑制受精、早期胚胎发育和免疫复合物吞噬内化。
仅供科研使用。不可用于诊断程序。
规格
分子式C22H31NO5S
数量100 μg
建议的储存条件在冷冻冰箱中（-5°C 至 -30°C）储存
运输条件室温
子细胞定位肌动蛋白、细胞骨架
物理形态实心
产品类型红海海绵素 A
Unit SizeEach
引用和文献 (336)
引用和文献
Abstract
A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor.
Journal:Nature
PubMed ID:10499588
Caveolin-associated filamentous actin (Cav-actin) defines a novel F-actin structure in adipocytes.
Journal:J Biol Chem
PubMed ID:12039946
Dynamic actin remodeling has been implicated in the translocation of the insulin-responsive glucose transporter 4 (GLUT4) to the plasma membrane in adipocytes. Here we show that fully differentiated 3T3L1 adipocytes have unique cortical filamentous actin structure, designated Cav-actin (caveolae-associated F-actin). During 3T3L1 adipocyte differentiation, rhodamine-phalloidin staining demonstrated the formation of
Actin filament cross-linking by MARCKS: characterization of two actin-binding sites within the phosphorylation site domain.
Journal:J Biol Chem
PubMed ID:11294839
We recently identified conformational changes that occur upon phosphorylation of myristoylated alanine-rich protein kinase C substrate (MARCKS) that preclude efficient cross-linking of actin filaments (Bubb, M. R., Lenox, R. H., and Edison, A. S. (1999) J. Biol. Chem. 274, 36472-36478). These results implied that the phosphorylation site domain of MARCKS
Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts.
Journal:Am J Physiol Cell Physiol
PubMed ID:15075215
Sphingosine 1-phosphate (S1P), a bioactive phospholipid, simultaneously induces actin cytoskeletal rearrangements and activation of matriptase, a membrane-associated serine protease in human mammary epithelial cells. In this study, we used a monoclonal antibody selective for activated, two-chain matriptase to examine the functional relationship between these two S1P-induced events. Ten minutes after
Differential control of clustering of the sodium channels Na(v)1.2 and Na(v)1.6 at developing CNS nodes of Ranvier.
Journal:Neuron
PubMed ID:11343648
'Na(v)1.6 is the main sodium channel isoform at adult nodes of Ranvier. Here, we show that Na(v)1.2 and its beta2 subunit, but not Na(v)1.6 or beta1, are clustered in developing central nervous system nodes and that clustering of Na(v)1.2 and Na(v)1.6 is differentially controlled. Oligodendrocyte-conditioned medium is sufficient to induce