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引用和文献 (51)
Invitrogen™
MANT-GDP（2'-（或-3'）-O-（N-甲基氨茴酰）鸟苷 5'-二磷酸二钠盐）
核苷类似物 MANT GDP 的核糖基团经过修饰。MANT 荧光基团及其附着位置的紧凑性使得核苷类似物几乎不会干扰核苷酸-蛋白质相互作用。由于 MANT 荧光对荧光基团的环境敏感，因此可以直接检测核苷酸-蛋白质相互作用。MANT了解更多信息
| 货号 | 数量 |
|---|---|
| M12414 | 400 µL |
货号 M12414
价格（CNY)
4,552.00
飞享价
Ends: 31-Dec-2025
6,171.00共减 1,619.00 (26%)
Each
数量:
400 µL
价格（CNY)
4,552.00
飞享价
Ends: 31-Dec-2025
6,171.00共减 1,619.00 (26%)
Each
核苷类似物 MANT GDP 的核糖基团经过修饰。MANT 荧光基团及其附着位置的紧凑性使得核苷类似物几乎不会干扰核苷酸-蛋白质相互作用。由于 MANT 荧光对荧光基团的环境敏感，因此可以直接检测核苷酸-蛋白质相互作用。MANT 核苷酸是用于检测核苷酸结合蛋白的结构及酶活性的重要探针。
仅供科研使用。不可用于诊断程序。
规格
标记方法化学标记、直接标记
标签或染料MANT（N-甲基氨茴酰）
产品类型MANT-GDP
数量400 µL
运输条件湿冰
最大浓度5 mM
Unit SizeEach
内容与储存
在冷冻冰箱（-5°C 至 -30°C）中避光储存。
引用和文献 (51)
引用和文献
Abstract
Journal:
PubMed ID:11063593
The role of Mg2+ cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins.
Journal:J Biol Chem
PubMed ID:10843989
'The biological activities of Rho family GTPases are controlled by their guanine nucleotide binding states in cells. Here we have investigated the role of Mg(2+) cofactor in the guanine nucleotide binding and hydrolysis processes of the Rho family members, Cdc42, Rac1, and RhoA. Differing from Ras and Rab proteins, which
Kinetics of Cdc42 membrane extraction by Rho-GDI monitored by real-time fluorescence resonance energy transfer.
Journal:Biochemistry
PubMed ID:10026253
'The mechanisms underlying the ability of the Rho-GDP dissociation inhibitor (RhoGDI) to elicit the release of Rho-related GTP-binding proteins from membranes is currently unknown. In this report, we have set out to address this issue by using fluorescence resonance energy transfer approaches to examine the functional interactions of the RhoGDI
Biochemical analysis of SopE from Salmonella typhimurium, a highly efficient guanosine nucleotide exchange factor for RhoGTPases.
Journal:J Biol Chem
PubMed ID:10521431
'RhoGTPases are key regulators of eukaryotic cell physiology. The bacterial enteropathogen Salmonella typhimurium modulates host cell physiology by translocating specific toxins into the cytoplasm of host cells that induce responses such as apoptotic cell death in macrophages, the production of proinflammatory cytokines, the rearrangement of the host cell actin cytoskeleton
Alanine scan mutagenesis of the switch I domain of the Caulobacter crescentus CgtA protein reveals critical amino acids required for in vivo function.
Journal:Mol Microbiol
PubMed ID:11251813
'The Caulobacter crescentus CgtA protein is a member of the Obg/GTP1 subfamily of monomeric GTP-binding proteins. In vitro, CgtA displays moderate affinity for both GDP and GTP and displays rapid exchange rate constants for either nucleotide, indicating that the guanine nucleotide-binding and exchange properties of CgtA are different from those