Spontaneous and plasma factor-mediated transfer of pyrenyl cerebrosides between model and native lipoproteins.
Authors:Via DP, Massey JB, Vignale S, Kundu SK, Marcus DM, Pownall HJ, Gotto AM
Journal:Biochim Biophys Acta
PubMed ID:3931685
'A series of pyrenyl glucocerebrosides was synthesized by reacylation of psychosine with pyrene-labeled fatty acids having 3-11 methylene units. When incorporated into model high-density lipoproteins consisting of dimyristoylphosphatidylcholine-apolipoprotein A-II complexes and incubated with unlabeled complexes, these lipids exhibited spontaneous transfer. Half times of transfer varied from 1.5 min to 365 ... More