In vivo real-time, multicolor, quantum dot lymphatic imaging.
Authors:Kosaka N, Ogawa M, Sato N, Choyke PL, Kobayashi H,
Journal:J Invest Dermatol
PubMed ID:19536144
'The lymphatic network is complex and difficult to visualize in real-time in vivo. Moreover, the direction of flow within lymphatic networks is often unpredictable especially in areas with well-developed ' ... More
Simultaneous multicolor imaging of five different lymphatic basins using quantum dots.
Authors:Kobayashi H, Hama Y, Koyama Y, Barrett T, Regino CA, Urano Y, Choyke PL
Journal:Nano Lett
PubMed ID:17530812
Quantum dots can be used to perform multicolor images with high fluorescent intensity and are of a nanosize suitable for lymphatic imaging via direct interstitial injection. Here simultaneous multicolor in vivo wavelength-resolved spectral fluorescence lymphangiography is shown using five quantum dots with similar physical sizes but different emission spectra. This ... More
Cholera toxin B conjugated quantum dots for live cell labeling.
Cholera toxin subunit B (CTB)--quantum dot conjugates were developed for labeling mammalian cells. The conjugates were internalized by all tested cell lines into small vesicles dispersed throughout the cytoplasm, while commercially available polyarginine conjugates rapidly accumulated in large perinuclear endosomes. Although a large proportion of CTB conjugates eventually also accumulated ... More