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Invitrogen
Versican Recombinant Rabbit Monoclonal Antibody (24GB2380)
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FIGURE: 1 / 4
Versican Antibody (MA5-57840) in ICC/IF
Immunocytochemical staining of Versican in HepG2 cells using Versican Recombinant Monoclonal Antibody (Product # MA5-57840) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; Versican was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Product Details
MA5-57840
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB2380
Immunogen
A synthesized peptide derived from human Versican (aa 3200-3280)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
Versican is a member of the family of large aggregating proteoglycans (also including aggrecan, brevican, and neurocan). The protein shows wide tissue distribution which includes fibrous, articular, and elastic cartilages, as well as nervous, epidermal, arterial, and loose connective tissues. Versican V1 has been shown to enhance cell proliferation, and also induce cell transformation and protect cells from apoptosis. This was demonstrated through its ability to downregulate the expression of proapoptotic Bad. Versican's existence as a extracellular matrix protein in human airways has also lead to the discovery of an inflammatory role in asthmatics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chondroitin sulfate proteoglycan 2; chondroitin sulfate proteoglycan 2 (versican); Chondroitin sulfate proteoglycan core protein 2; GHAP; Glial hyaluronate-binding protein; heart defect; Large fibroblast proteoglycan; PG-M; PG-M core protein; PGM; V1 Neo; Versican core protein; Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M); versican proteoglycan; Versican V0; WGN 1
Gene Aliases: 5430420N07Rik; 9430051N09; CSPG2; DPEAAE; ERVR; GHAP; hdf; NG2; PG-M; PG-M(V0); PG-M(V1); VCAN; WGN; WGN1
UniProt ID: (Human) P13611, (Rat) Q9ERB4
Entrez Gene ID: (Human) 1462, (Mouse) 13003, (Rat) 114122
skeletal system development
osteoblast differentiation
cell adhesion
multicellular organism development
central nervous system development
cell recognition
extracellular matrix organization
glycosaminoglycan metabolic process
chondroitin sulfate biosynthetic process
chondroitin sulfate catabolic process
dermatan sulfate biosynthetic process
heart development
glial cell migration
regulation of phosphoprotein phosphatase activity
response to wounding
axon regeneration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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