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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Hexachlorobenzene (HCB) is an organochlorine compound known for its persistence in the environment and its bioaccumulation in living organisms. It was initially used as a fungicide but has been banned due to its slow biodegradation and potential health risks. Structurally, HCB is a chlorinated aromatic compound with six chlorine atoms attached to a benzene ring, making it highly stable and resistant to breakdown. Functionally, HCB acts through the aryl hydrocarbon receptor (AhR), leading to translocation to the nucleus and modulation of gene expression, similar to dioxin-like compounds. This interaction can trigger various cellular responses, including activation of c-Src kinase activity. Despite its ban, HCB residues are still found in the environment, posing risks to human health and wildlife.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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