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FIGURE: 1 / 8
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: 31 kDa-transforming protein; 31kDa Transforming Protein; hCG_25181; SPIA; Transcription factor PU.1; Transcription Factor spi1
Gene Aliases: SPI1
Entrez Gene ID: (Human) 6688
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