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          System Message

          OKCancel
          LOADING ...
          See other FMR1 SIRNA Assays ›
          Gene Symbol:
          FMR1
          Gene Name:
          fragile X mental retardation 1
          Gene Aliases:
          FMRP, FRAXA, POF, POF1
          Chromosome Location:
          Chr.X: 147911951 - 147951127 on Build GRCh38
          UniGene ID:
          Hs.103183
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 10919

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: FMR1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001185075.1 NP_001172004.1 4, 5 491
          NM_001185076.1 NP_001172005.1 4, 5 491
          NM_001185081.1 NP_001172010.1 4, 5 491
          NM_001185082.1 NP_001172011.1 4, 5 491
          NM_002024.5 NP_002015.1 4, 5 491
          NR_033699.1 4, 5 491
          NR_033700.1 4, 5 491
          GenBank mRNA BC038998.1 - 4, 5 456
          BC086957.1 - 4, 5 521 30347992
          BQ213316.1 - 4, 5 443
          KC774027.1 - 4, 5 324
          KC774028.1 - 4, 5 324
          KC774029.1 - 4, 5 324
          KF856234.1 - 4, 5 324
          KJ534836.1 - 4, 5 262
          KJ534837.1 - 4, 5 262
          KJ534838.1 - 4, 5 262
          KM091457.1 - 4, 5 324
          KM091458.1 - 4, 5 324
          KM091459.1 - 4, 5 324
          M67468.1 - 4, 5 457
          S65791.1 - 4, 5 481
          X69962.1 - 4, 5 481

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_052804, XM_006229530, XM_006229531, XM_006229535, XM_008773597, and others.
          This siRNA also targets the following transcripts in Mouse: NM_008031, NM_001290424, AK053701, AK080948, AK053211, and others.

          Panther Classification:

          Molecular Function -

          translation factor

          Gene Ontology Categories:

          Function(s) Process(es)

          regulation of alternative mRNA splicing, via spliceosome
          positive regulation of receptor internalization
          mRNA processing
          cellular response to DNA damage stimulus
          glutamate receptor signaling pathway
          RNA splicing
          negative regulation of translation
          gene silencing by RNA
          positive regulation of histone phosphorylation
          cellular response to UV
          regulation of mRNA stability
          modulation by host of viral RNA genome replication
          positive regulation of translation
          negative regulation of translational initiation
          regulation of neurotransmitter secretion
          mRNA transport
          regulation of filopodium assembly
          positive regulation of filopodium assembly
          regulation of gene silencing by miRNA
          regulation of dendritic spine development
          positive regulation of dendritic spine development
          cellular response to hydroxyurea
          cellular response to virus
          regulation of neuronal action potential
          negative regulation of long term synaptic depression
          positive regulation of intracellular transport of viral material
          negative regulation of voltage-gated calcium channel activity
          positive regulation of proteasomal protein catabolic process
          positive regulation of mRNA binding
          negative regulation of synaptic vesicle exocytosis
          positive regulation of gene silencing by miRNA
          negative regulation of cytoplasmic translation
          positive regulation of response to DNA damage stimulus
          G-quadruplex RNA binding
          chromatin binding
          RNA binding
          mRNA binding
          mRNA 3'-UTR binding
          protein binding
          microtubule binding
          poly(U) RNA binding
          translation repressor activity
          translation initiation factor binding
          RNA strand annealing activity
          poly(G) binding
          methylated histone binding
          siRNA binding
          miRNA binding
          RNA stem-loop binding
          identical protein binding
          protein homodimerization activity
          ribosome binding
          ion channel binding
          poly(A) RNA binding
          dynein binding
          protein heterodimerization activity
          mRNA 5'-UTR binding
          sequence-specific mRNA binding

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