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          System Message

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          LOADING ...
          See other RIPK2 SIRNA Assays ›
          Gene Symbol:
          RIPK2
          Gene Name:
          receptor interacting serine/threonine kinase 2
          Gene Aliases:
          CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
          Chromosome Location:
          Chr.8: 89757747 - 89791064 on Build GRCh38
          UniGene ID:
          Hs.103755
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 137245

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 286.00
          Your Price
          Online offer: 277.65
          277.65
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: RIPK2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_003821.5 NP_003812.1 11 1738
          XM_005251092.3 XP_005251149.1 10 1548
          XM_011517357.2 XP_011515659.1 9 1071
          GenBank mRNA AF027706.1 - 11 1648
          AF064824.1 - 11 1666
          AF078530.1 - 11 1424
          AK075213.1 - 11 1642
          AK301448.1 - 10 1497
          AY358813.1 - 10 1495
          AY358814.1 - 11 1675
          AY524045.1 - 11 1511
          BC004553.2 - 11 1626 4026156
          KU178437.1 - 11 1424
          KU178438.1 - 10 1270

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          More Information


          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPK activity
          positive regulation of cytokine-mediated signaling pathway
          adaptive immune response
          apoptotic process
          inflammatory response
          signal transduction
          I-kappaB kinase/NF-kappaB signaling
          JNK cascade
          positive regulation of peptidyl-threonine phosphorylation
          peptidyl-tyrosine phosphorylation
          positive regulation of protein ubiquitination
          lipopolysaccharide-mediated signaling pathway
          positive regulation of chemokine production
          positive regulation of interferon-alpha production
          positive regulation of interferon-beta production
          positive regulation of interferon-gamma production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-2 production
          positive regulation of interleukin-6 production
          positive regulation of tumor necrosis factor production
          positive regulation of immature T cell proliferation
          positive regulation of peptidyl-serine phosphorylation
          toll-like receptor 2 signaling pathway
          toll-like receptor 4 signaling pathway
          T cell proliferation
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          response to exogenous dsRNA
          innate immune response
          positive regulation of T-helper 1 cell differentiation
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of JNK cascade
          positive regulation of alpha-beta T cell proliferation
          positive regulation of peptidyl-tyrosine phosphorylation
          defense response to Gram-positive bacterium
          T cell receptor signaling pathway
          positive regulation of NF-kappaB transcription factor activity
          positive regulation of ERK1 and ERK2 cascade
          nucleotide-binding oligomerization domain containing signaling pathway
          nucleotide-binding oligomerization domain containing 1 signaling pathway
          nucleotide-binding oligomerization domain containing 2 signaling pathway
          response to interleukin-1
          response to interleukin-12
          response to interleukin-18
          cellular response to lipoteichoic acid
          cellular response to peptidoglycan
          cellular response to muramyl dipeptide
          positive regulation of xenophagy
          protein serine/threonine kinase activity
          non-membrane spanning protein tyrosine kinase activity
          signal transducer activity
          receptor binding
          protein binding
          ATP binding
          LIM domain binding
          protein homodimerization activity
          CARD domain binding

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