Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Products
    • Antibodies
    • Custom DNA Oligos
    • GeneArt Gene Synthesis Instant Designer
    • TaqMan Assay and Array Search
    • PCR Equipment and Supplies
    • Chromatography Columns and Cartridges
    • Lab Centrifuges
    • Molecular Biology Reagents and Kits
    • Lab Plasticware and Supplies
    • See all product categories
  • Applications
    • Chromatography
    • Cell Culture
    • Real-Time PCR
    • Mass Spectrometry
    • Lab Plasticware and Supplies
    • Electron Microscopy
    • Protein Biology
    • PCR
    • RNAi
    • Environmental
    • See all applications and techniques
  • Services
    • Custom Services
    • Enterprise-Level Lab Informatics
    • Enterprise Services
    • Financial and Leasing Services
    • Instrument Services
    • OEM and Commercial Supply
    • Training Services
    • 360° CDMO and CRO Solutions
    • CDMO Services
    • CRO Services
    • See all services
  • Help and Support
    • Learning Centers
    • Contact Us
    • Change Location
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search

Search All
Search button
          • Contact Us
          • Quick Order
          • Sign in
            Sign in
            Don't have an account ? Create Account
            • Account
            • Check Order Status
            • AR Statement & Invoice Inquiry
            • Custom Products & Projects
            • Instrument Management
          This product has been added to your favorites list. Go to My Favorites

          System Message

          OKCancel
          LOADING ...
          See other IRS1 SIRNA Assays ›
          Gene Symbol:
          IRS1
          Gene Name:
          insulin receptor substrate 1
          Gene Aliases:
          HIRS-1
          Chromosome Location:
          Chr.2: 226731317 - 226798790 on Build GRCh38
          UniGene ID:
          Hs.471508
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 145282

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

          LOADING...
          ×
          Back To Top

          siRNA Details

          Gene Symbol: IRS1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_005544.2 NP_005535.1 1 1500
          GenBank mRNA BC053895.1 - 1 1500 6144252
          S62539.1 - 1 2468

          Back To Top

          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          signal transduction
          positive regulation of cell proliferation
          insulin receptor signaling pathway
          positive regulation of glucose metabolic process
          phosphatidylinositol 3-kinase signaling
          regulation of phosphatidylinositol 3-kinase signaling
          positive regulation of fatty acid beta-oxidation
          response to insulin
          cellular response to insulin stimulus
          phosphatidylinositol-3-phosphate biosynthetic process
          glucose homeostasis
          response to peptide hormone
          positive regulation of GTPase activity
          positive regulation of phosphatidylinositol 3-kinase activity
          positive regulation of glycogen biosynthetic process
          positive regulation of glucose import
          negative regulation of insulin receptor signaling pathway
          positive regulation of insulin receptor signaling pathway
          negative regulation of insulin secretion
          phosphatidylinositol phosphorylation
          insulin-like growth factor receptor signaling pathway
          phosphatidylinositol-mediated signaling
          positive regulation of glucose import in response to insulin stimulus
          signal transducer activity
          transmembrane receptor protein tyrosine kinase adaptor activity
          protein kinase C binding
          Ras guanyl-nucleotide exchange factor activity
          insulin receptor binding
          insulin-like growth factor receptor binding
          protein binding
          1-phosphatidylinositol-3-kinase activity
          SH2 domain binding
          phosphatidylinositol 3-kinase binding
          phosphatidylinositol-4,5-bisphosphate 3-kinase activity

          Back To Top

          Related Products

          • Anti-GAPDH, Mouse Monoclonal 6C5
          • Anti-β-Actin, Mouse Monoclonal AC-15
          • TaqMan® Gene Expression Cells-to-CT™
          • Neon™ Transfection System 100 µL Kit
          • Lipofectamine™ RNAiMAX Transfection Reagent
          • Invivofectamine 2.0
          • Lipofectamine™ 2000 Transfection Reagent
          • Neon™ Transfection System
          Ordering Plus Icon Minus Icon
          • Order Status
          • Order Help
          • Quick Order
          • Supply Center
          • eProcurement
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us - 400 820 8982
          • Technical Support Centers
          • Documents and Certificates
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Webinars
          • Social Media
          About Thermo Fisher Plus Icon Minus Icon
          • About Us About Us
          • Careers Careers
          • Investors Investors
          • News News
          • Social Responsibility Social Responsibility
          • Trademarks
          • Policies and Notices
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Policy
          • Price & Freight Policy
          © 2006-2026 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          China flag icon
          China
          本网站销售的所有产品均不得用于人类或动物之临床诊断或治疗,仅可用于工业或者科研等非医疗目的。
             电子营业执照 | 经营证照公示 | ICP备案号:沪ICP备11003924号 | 沪公网安备 31011502006935号

          Your items have has been added!


          Host server : magellan-search-blue-55ff9ddd88-lq2bv:80/100.66.79.31:80.
          git-commit: d366ff9721d93504b2ac26a183b2b3e3d0e7d9ec
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.42.0-2026.01.03-1.0