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          System Message

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          LOADING ...
          See other IRS1 SIRNA Assays ›
          Gene Symbol:
          IRS1
          Gene Name:
          insulin receptor substrate 1
          Gene Aliases:
          HIRS-1
          Chromosome Location:
          Chr.2: 226731317 - 226798790 on Build GRCh38
          UniGene ID:
          Hs.471508
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 16504

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: IRS1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_005544.2 NP_005535.1 2 4687
          GenBank mRNA BC053895.1 - 2 4687 6144252
          S62539.1 - 2 5655

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          signal transduction
          positive regulation of cell proliferation
          insulin receptor signaling pathway
          positive regulation of glucose metabolic process
          phosphatidylinositol 3-kinase signaling
          regulation of phosphatidylinositol 3-kinase signaling
          positive regulation of fatty acid beta-oxidation
          response to insulin
          cellular response to insulin stimulus
          phosphatidylinositol-3-phosphate biosynthetic process
          glucose homeostasis
          response to peptide hormone
          positive regulation of GTPase activity
          positive regulation of phosphatidylinositol 3-kinase activity
          positive regulation of glycogen biosynthetic process
          positive regulation of glucose import
          negative regulation of insulin receptor signaling pathway
          positive regulation of insulin receptor signaling pathway
          negative regulation of insulin secretion
          phosphatidylinositol phosphorylation
          insulin-like growth factor receptor signaling pathway
          phosphatidylinositol-mediated signaling
          positive regulation of glucose import in response to insulin stimulus
          signal transducer activity
          transmembrane receptor protein tyrosine kinase adaptor activity
          protein kinase C binding
          Ras guanyl-nucleotide exchange factor activity
          insulin receptor binding
          insulin-like growth factor receptor binding
          protein binding
          1-phosphatidylinositol-3-kinase activity
          SH2 domain binding
          phosphatidylinositol 3-kinase binding
          phosphatidylinositol-4,5-bisphosphate 3-kinase activity

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