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          System Message

          OKCancel
          LOADING ...
          See other NKX2-5 SIRNA Assays ›
          Gene Symbol:
          NKX2-5
          Gene Name:
          NK2 homeobox 5
          Gene Aliases:
          CHNG5, CSX, CSX1, HLHS2, NKX2.5, NKX2E, NKX4-1, VSD3
          Chromosome Location:
          Chr.5: 173232104 - 173235312 on Build GRCh38
          UniGene ID:
          Hs.54473
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 45082

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: NKX2-5
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001166175.1 NP_001159647.1 2 1627
          NM_001166176.1 NP_001159648.1 2 1590
          NM_004387.3 NP_004378.1 2 1335
          GenBank mRNA AK290615.1 - 2 1227
          BC025711.1 - 2 1213 5225103
          U34962.1 - 2 1282

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          More Information


          Panther Classification:

          Molecular Function -

          homeodomain transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          vasculogenesis
          heart looping
          heart morphogenesis
          outflow tract septum morphogenesis
          cardiac conduction system development
          bundle of His development
          Purkinje myocyte differentiation
          cardiac ventricle formation
          right ventricular cardiac muscle tissue morphogenesis
          ventricular trabecula myocardium morphogenesis
          apoptotic process involved in heart morphogenesis
          septum secundum development
          proepicardium development
          pulmonary myocardium development
          transcription from RNA polymerase II promoter
          adult heart development
          positive regulation of cell proliferation
          negative regulation of cardiac muscle cell apoptotic process
          positive regulation of transcription via serum response element binding
          positive regulation of sodium ion transport
          negative regulation of myotube differentiation
          hemopoiesis
          cell differentiation
          BMP signaling pathway
          thyroid gland development
          embryonic heart tube development
          negative regulation of apoptotic process
          sarcomere organization
          positive regulation of neuron differentiation
          positive regulation of heart contraction
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          spleen development
          positive regulation of cardioblast differentiation
          ventricular cardiac myofibril assembly
          cardiac muscle cell differentiation
          cardiac muscle tissue morphogenesis
          atrial cardiac muscle cell development
          ventricular cardiac muscle cell development
          regulation of cardiac muscle contraction
          pharyngeal system development
          cardiac muscle cell proliferation
          regulation of cardiac muscle cell proliferation
          cardiac muscle contraction
          canonical Wnt signaling pathway
          positive regulation of transcription initiation from RNA polymerase II promoter
          heart trabecula formation
          ventricular septum morphogenesis
          atrial septum morphogenesis
          atrioventricular node cell development
          atrioventricular node cell fate commitment
          embryonic heart tube left/right pattern formation
          negative regulation of canonical Wnt signaling pathway
          regulation of cardiac conduction
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          RNA polymerase II transcription cofactor activity
          transcriptional activator activity, RNA polymerase II transcription factor binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          DNA binding
          chromatin binding
          transcription factor activity, sequence-specific DNA binding
          transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
          protein binding
          transcription factor binding
          serum response element binding
          protein homodimerization activity
          sequence-specific DNA binding
          transcription regulatory region DNA binding
          protein heterodimerization activity

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