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          System Message

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          LOADING ...
          See other TWIST1 SIRNA Assays ›
          Gene Symbol:
          TWIST1
          Gene Name:
          twist family bHLH transcription factor 1
          Gene Aliases:
          ACS3, BPES2, BPES3, CRS, CRS1, CSO, SCS, TWIST, bHLHa38
          Chromosome Location:
          Chr.7: 19113047 - 19117672 on Build GRCh38
          UniGene ID:
          Hs.644998
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS186976
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: TWIST1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000474.3 NP_000465.1 1 869
          XM_011515496.1 XP_011513798.1 1 616
          GenBank mRNA BC036704.2 - 1 869 4125830
          X99268.1 - 1 640

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_053530, BC166412, AF266260.
          This siRNA also targets the following transcripts in Mouse: NM_011658, BC083139, BC033434, M63650.

          Panther Classification:

          Molecular Function -

          basic helix-loop-helix transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          ossification
          osteoblast differentiation
          in utero embryonic development
          neuron migration
          neural tube closure
          aortic valve morphogenesis
          mitral valve morphogenesis
          endocardial cushion morphogenesis
          cardiac neural crest cell migration involved in outflow tract morphogenesis
          transcription, DNA-templated
          muscle organ development
          positive regulation of gene expression
          positive regulation of epithelial to mesenchymal transition
          negative regulation of phosphatidylinositol 3-kinase signaling
          regulation of bone mineralization
          positive regulation of fatty acid beta-oxidation
          negative regulation of tumor necrosis factor production
          positive regulation of tumor necrosis factor production
          negative regulation of histone phosphorylation
          negative regulation of histone acetylation
          embryonic forelimb morphogenesis
          embryonic hindlimb morphogenesis
          negative regulation of peroxisome proliferator activated receptor signaling pathway
          outer ear morphogenesis
          odontogenesis
          embryonic digit morphogenesis
          negative regulation of apoptotic process
          negative regulation of sequence-specific DNA binding transcription factor activity
          negative regulation of DNA damage response, signal transduction by p53 class mediator
          negative regulation of osteoblast differentiation
          positive regulation of angiogenesis
          negative regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          rhythmic process
          negative regulation of skeletal muscle tissue development
          embryonic cranial skeleton morphogenesis
          positive regulation of epithelial cell proliferation
          palate development
          cranial suture morphogenesis
          embryonic camera-type eye formation
          eyelid development in camera-type eye
          cellular response to growth factor stimulus
          cellular response to hypoxia
          positive regulation of monocyte chemotactic protein-1 production
          positive regulation of DNA-templated transcription, initiation
          positive regulation of cell motility
          negative regulation of oxidative phosphorylation uncoupler activity
          positive regulation of transcription regulatory region DNA binding
          negative regulation of cellular senescence
          positive regulation of interleukin-6 secretion
          negative regulation of double-strand break repair
          cell proliferation involved in heart valve development
          positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          protein binding
          transcription factor binding
          protein domain specific binding
          protein homodimerization activity
          bHLH transcription factor binding
          protein heterodimerization activity
          E-box binding

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