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          System Message

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          LOADING ...
          See other IRS1 SIRNA Assays ›
          Gene Symbol:
          Irs1
          Gene Name:
          insulin receptor substrate 1
          Gene Aliases:
          G972R, IRS-1
          Chromosome Location:
          Chr.1: 82233105 - 82291439 on Build GRCm38
          UniGene ID:
          Mm.4952
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID MSS205507
          Size 20 nmol
          Availability Made To Order
          Catalog # 1320001
          Price Contact Us
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Irs1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_010570.4 NP_034700.2 1 1150
          GenBank mRNA AK045317.1 - 1 1128
          AK142242.1 - 1 617
          L24563.1 - 1 204
          X69722.1 - 1 676

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_012969, X58375.

          Gene Ontology Categories:

          Function(s) Process(es)

          positive regulation of mesenchymal cell proliferation
          signal transduction
          insulin receptor signaling pathway
          regulation of gene expression
          positive regulation of glucose metabolic process
          phosphatidylinositol 3-kinase signaling
          lipid catabolic process
          insulin secretion
          positive regulation of cell migration
          mammary gland development
          response to caffeine
          positive regulation of fatty acid beta-oxidation
          response to insulin
          cellular response to insulin stimulus
          protein localization to nucleus
          positive regulation of phosphorylation
          response to peptide hormone
          protein kinase B signaling
          positive regulation of phosphatidylinositol 3-kinase activity
          positive regulation of glycogen biosynthetic process
          positive regulation of glucose import
          negative regulation of insulin receptor signaling pathway
          positive regulation of insulin receptor signaling pathway
          negative regulation of insulin secretion
          insulin-like growth factor receptor signaling pathway
          protein heterooligomerization
          positive regulation of glucagon secretion
          negative regulation of somatostatin secretion
          positive regulation of glucose import in response to insulin stimulus
          signal transducer activity
          transmembrane receptor protein tyrosine kinase adaptor activity
          protein kinase C binding
          insulin receptor binding
          insulin-like growth factor receptor binding
          protein binding
          protein kinase binding
          protein domain specific binding
          SH2 domain binding
          phosphatidylinositol 3-kinase binding

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