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          System Message

          OKCancel
          LOADING ...
          See other TGFBR1 SIRNA Assays ›
          Gene Symbol:
          TGFBR1
          Gene Name:
          transforming growth factor beta receptor 1
          Gene Aliases:
          AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, TGFR-1, tbetaR-I
          Chromosome Location:
          Chr.9: 99104038 - 99154192 on Build GRCh38
          UniGene ID:
          Hs.494622
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s14071
          Validated

          Purification
          Size
          Availability Inventoried
          Catalog # 4390824
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: TGFBR1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001130916.2 NP_001124388.1 6 1101
          NM_001306210.1 NP_001293139.1 7 1344
          NM_004612.3 NP_004603.1 7 1332
          XM_011518948.2 XP_011517250.1 7 1259
          XM_011518949.2 XP_011517251.1 7 1187
          XM_011518950.2 XP_011517252.1 6 4289
          XM_017015063.1 XP_016870552.1 7 1222
          GenBank mRNA AJ619019.2 - 7 1303
          AK302059.1 - 7 1218
          AK302234.1 - 7 1205
          BC071181.1 - 6 1079 30344890
          L11695.1 - 7 1291

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_012775, XM_008763706, XM_006238153, XM_006238030, BC087035, and others.

          Matching Taqman Gene Expression Assay:


          Hs00610319_m1

          Panther Classification:

          Molecular Function -

          serine/threonine protein kinase receptor

          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPKK activity
          skeletal system development
          angiogenesis
          in utero embryonic development
          kidney development
          blastocyst development
          epithelial to mesenchymal transition
          negative regulation of endothelial cell proliferation
          positive regulation of endothelial cell proliferation
          lens development in camera-type eye
          ventricular trabecula myocardium morphogenesis
          ventricular compact myocardium morphogenesis
          proepicardium development
          regulation of transcription, DNA-templated
          protein phosphorylation
          apoptotic process
          cell cycle arrest
          signal transduction
          transforming growth factor beta receptor signaling pathway
          heart development
          positive regulation of cell proliferation
          germ cell migration
          male gonad development
          post-embryonic development
          anterior/posterior pattern specification
          regulation of epithelial to mesenchymal transition
          positive regulation of epithelial to mesenchymal transition
          positive regulation of pathway-restricted SMAD protein phosphorylation
          peptidyl-serine phosphorylation
          peptidyl-threonine phosphorylation
          signal transduction by protein phosphorylation
          collagen fibril organization
          positive regulation of cell growth
          positive regulation of cell migration
          negative regulation of transforming growth factor beta receptor signaling pathway
          regulation of protein ubiquitination
          negative regulation of chondrocyte differentiation
          activin receptor signaling pathway
          intracellular signal transduction
          wound healing
          endothelial cell activation
          extracellular structure organization
          regulation of protein binding
          endothelial cell migration
          positive regulation of transcription, DNA-templated
          thymus development
          neuron fate commitment
          embryonic cranial skeleton morphogenesis
          skeletal system morphogenesis
          mesenchymal cell differentiation
          artery morphogenesis
          cell motility
          positive regulation of cellular component movement
          positive regulation of filopodium assembly
          positive regulation of stress fiber assembly
          positive regulation of protein kinase B signaling
          parathyroid gland development
          palate development
          pharyngeal system development
          regulation of cardiac muscle cell proliferation
          cardiac epithelial to mesenchymal transition
          pathway-restricted SMAD protein phosphorylation
          positive regulation of SMAD protein import into nucleus
          ventricular septum morphogenesis
          coronary artery morphogenesis
          response to cholesterol
          cellular response to transforming growth factor beta stimulus
          positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
          positive regulation of occluding junction disassembly
          positive regulation of apoptotic signaling pathway
          negative regulation of extrinsic apoptotic signaling pathway
          protein kinase activity
          protein serine/threonine kinase activity
          receptor signaling protein serine/threonine kinase activity
          transforming growth factor beta-activated receptor activity
          transforming growth factor beta receptor activity, type I
          receptor signaling protein activity
          type II transforming growth factor beta receptor binding
          protein binding
          ATP binding
          growth factor binding
          SMAD binding
          metal ion binding
          transforming growth factor beta binding
          I-SMAD binding

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