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          System Message

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          LOADING ...
          See other STAT3 SIRNA Assays ›
          Gene Symbol:
          Stat3
          Gene Name:
          signal transducer and activator of transcription 3
          Gene Aliases:
          1110034C02Rik, AW109958, Aprf
          Chromosome Location:
          Chr.11: 100886810 - 100939570 on Build GRCm38
          UniGene ID:
          Mm.249934
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID s74452

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Stat3
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_011486.4 NP_035616.1 11 1356
          NM_213659.2 NP_998824.1 11 1356
          NM_213660.2 NP_998825.1 11 1356
          GenBank mRNA AK145486.1 - 11 1212
          AK153005.1 - 11 1268
          AK153472.1 - 11 1268
          AY299489.1 - 10 1083
          AY299490.1 - 10 1083
          BC003806.1 - 11 1244 3593588
          BC019168.1 - 11 1260 4923137
          L29278.1 - 11 1335
          U06922.1 - 11 1145
          U08378.1 - 11 1223
          U30709.1 - 11 1249

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Human: NM_003150, NM_213662, NM_139276, L29277, AK297994, and others.
          This siRNA also targets the following transcripts in Rat: NM_012747, XM_006247258, XM_006247257, XM_006247259, X91810, and others.

          Panther Classification:

          Molecular Function -

          DNA-binding transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          temperature homeostasis
          eye photoreceptor cell differentiation
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          transcription from RNA polymerase II promoter
          protein import into nucleus
          acute-phase response
          signal transduction
          JAK-STAT cascade
          cell proliferation
          negative regulation of cell proliferation
          negative regulation of hydrogen peroxide biosynthetic process
          phosphorylation
          cytokine-mediated signaling pathway
          stem cell population maintenance
          sexual reproduction
          intracellular receptor signaling pathway
          response to estradiol
          cellular response to hormone stimulus
          response to cytokine
          regulation of multicellular organism growth
          glucose homeostasis
          eating behavior
          negative regulation of apoptotic process
          positive regulation of Notch signaling pathway
          negative regulation of glycolytic process
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          regulation of mitochondrial membrane permeability
          astrocyte differentiation
          radial glial cell differentiation
          growth hormone receptor signaling pathway
          JAK-STAT cascade involved in growth hormone signaling pathway
          negative regulation of cell death
          interleukin-6-mediated signaling pathway
          negative regulation of neuron death
          positive regulation of growth factor dependent skeletal muscle satellite cell proliferation
          positive regulation of ATP biosynthetic process
          negative regulation of neuron migration
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          RNA polymerase II repressing transcription factor binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          DNA binding
          transcription factor activity, sequence-specific DNA binding
          signal transducer activity
          RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
          protein binding
          transcription factor binding
          protein kinase binding
          protein phosphatase binding
          CCR5 chemokine receptor binding
          glucocorticoid receptor binding
          sequence-specific DNA binding
          transcription regulatory region DNA binding
          protein dimerization activity

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