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Invitrogen
Human/Mouse/Rat SERCA3 ATPase (aa 29-39) Synthetic Peptide
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Product Details
PEP-015
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Class
Synthetic
Type
Peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
50 µg
Purification
purified
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
PEP-015 is an 11 amino acid (amino acids 29-39) synthetic peptide whose sequence is from the amino end of SERCA3 that is conserved in mouse, rat, and human SERCA3. The sequence of this peptide is (amino to carboxy terminus): V-T-D-A-R-E-R-Y-G-P-N
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and serca3, catalog # PA1-910A. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.
Reconstitute with 0.1 mL of distilled water.
Target Information
ATP dependent calcium pumps are responsible in part for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium ATPases (SERCA). The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific isoform expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. SERCA3 has been found to co-express with SERCA2b in platelets, mast cells, lymphoid cells, and epithelial cells. Due to this pattern of expression it is referred to as the non-muscle form of SERCA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adenosine triphosphatase, calcium; ATPase, Ca(2+)-transporting, ubiquitous; ATPase, Ca++ transporting, ubiquitous; calcium ATPase; SERCA3f; Calcium pump 3; calcium-translocating P-type ATPase; sarco/endoplasmic reticulum Ca(2+)-ATPase 3-type Ca2+ pump; sarco/endoplasmic reticulum Ca2+ -ATPase; sarcoendoplasmic reticulum Ca2+ ATPase type 3; Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; SERCA3; SERCA3D; SERCA3E; SR Ca(2+)-ATPase 3; unnamed protein product
Gene Aliases: ATP2A3; SERCA3; SERCA3b
UniProt ID: (Human) Q93084, (Rat) P18596, (Mouse) Q64518
Entrez Gene ID: (Human) 489, (Rat) 25391, (Mouse) 53313
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