Amphiregulin Proteins

Amphiregulin recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: Bioactivity, Neutralization and Western blot control. These proteins are expressed in E. coli. Available Product Grades: Research Use Only. Gibco and... Amphiregulin recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: Bioactivity, Neutralization and Western blot control. These proteins are expressed in E. coli. Available Product Grades: Research Use Only. Gibco and Invitrogen proteins are some of the most frequently... Amphiregulin recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: Bioactivity, Neutralization and Western blot control. These proteins are expressed in E. coli. Available Product Grades: Research Use Only. Gibco and Invitrogen proteins are some of the most frequently published proteins. Amphiregulin Protein have been referenced in 20 publications which can be found in our reference library. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 3 proteins, including biologically active options. Not finding the exact protein, grade or size needed?... Amphiregulin recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: Bioactivity, Neutralization and Western blot control. These proteins are expressed in E. coli. Available Product Grades: Research Use Only. Gibco and Invitrogen proteins are some of the most frequently published proteins. Amphiregulin Protein have been referenced in 20 publications which can be found in our reference library. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 3 proteins, including biologically active options. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

Amphiregulin (AR) binds to EGF-Receptor (EGFR) with lower affinity than EGF. The mature secreted form AR is an 84-amino acid residue glycosylated polypeptide growth regulator, which is generated by proteolytic processing of a 252-amino acid transmembrane precursor. Seven different polypeptide ligands, which derive from distinct genes, are capable of binding to the extracellular domain of EGFR. These ligands include EGF, TGFalpha, AR, HB-EGF, cripto-1, epiregulin, and betacellulin. All of these growth factors contain a characteristic EGF-like domain which is defined by 6 evenly spaced cysteine residues that generate 3 loops through the formation of disulfide bonds. AR protein has been localized by immunohistochemistry to the epithelium of the colon, stomach, pancreas, breast, and placenta. AR is reportedly overexpressed in human cancers of breast, colon, stomach, and pancreas.

Synonyms

amphiregulin; amphiregulin B; AR; AREG; AREGB; colorectum cell-derived growth factor; CRDGF; Mcub; MGC13647; schwannoma-derived growth factor; SDGF

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Gibco

Human Amphiregulin Recombinant Protein, PeproTech®

Gibco

Human Amphiregulin Recombinant Protein, PeproTech®

Species

Human

Expression System

E. coli

Product Grade

Research Use Only

Application

Ctrl WB Ctrl Bioactivity

Price

Cat # 100-55B-50UG

Gibco

Mouse Amphiregulin Recombinant Protein, PeproTech®

Gibco

Mouse Amphiregulin Recombinant Protein, PeproTech®

Species

Mouse

Expression System

E. coli

Product Grade

Research Use Only

Application

Ctrl Bioactivity

Price

Cat # 315-36-50UG

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