IL-31 Proteins

IL-31 peptides and recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: Bioactivity, Neutralization, ELISA standard and Western blot control. These proteins are expressed in E. coli. Available Product Grades: Research... IL-31 peptides and recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: Bioactivity, Neutralization, ELISA standard and Western blot control. These proteins are expressed in E. coli. Available Product Grades: Research Use Only. Gibco and Invitrogen proteins are some of... IL-31 peptides and recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: Bioactivity, Neutralization, ELISA standard and Western blot control. These proteins are expressed in E. coli. Available Product Grades: Research Use Only. Gibco and Invitrogen proteins are some of the most frequently published proteins. IL-31 Protein have been referenced in 9 publications which can be found in our reference library. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 5 proteins, including biologically active options. Not finding the exact protein, grade or size needed?... IL-31 peptides and recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: Bioactivity, Neutralization, ELISA standard and Western blot control. These proteins are expressed in E. coli. Available Product Grades: Research Use Only. Gibco and Invitrogen proteins are some of the most frequently published proteins. IL-31 Protein have been referenced in 9 publications which can be found in our reference library. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 5 proteins, including biologically active options. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia, and skin lesions and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.

Synonyms

1700013B14Rik; IL31; IL-31; ILN; Interleukin; interleukin 31; interleukin-31

IL-31 Proteins

Protein Information

Synonyms

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