Antibodies that detect NSFL1C can be used in several scientific applications, including Western Blot, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry (Paraffin) and Immunohistochemistry. These antibodies target NSFL1C in Human, Mouse and Rat samples. Our NSFL1C polyclonal antibodies are developed in Rabbit. These antibodies have been verified by Knockdown to confirm specificity to NSFL1C. Find the NSFL1C antibody that fits your needs. Choose from 1 of 8 NSFL1C antibodies, which have been validated in experiments with 3 publications and 37 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more
p47, also known as NSFL1C, UBX1, UBXD10 or UBXN2C, is a 370 amino acid protein that localizes to both the nucleus and the golgi apparatus (specifically to golgi stacks) and contains one SEP domain and one UBX domain. Functioning as part of a ternary complex with VCP (a protein involved in the heterotypic fusion of transport vesicles with their target membranes) and Syntaxin 5, p47 interacts with and reduces the ATPase activity of VCP and is required for the fragmentation of golgi stacks during mitosis and for subsequent reassembly of golgi stacks after mitosis. p47 is subject to phosphorylation during mitosis, which inhibits p47-golgi interaction and is, therefore, required for proper golgi stack formation and cisternal regrowth. Human p47 shares 89% sequence identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of p47 exist due to alternative splicing events.
NSFL1 (p97) cofactor (p47); NSFL1 cofactor p47; p97 cofactor p47; RP4-776F14.2; SHP1 homolog; UBX domain-containing protein 2C