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PA5-16464 targets Calcitonin in IHC (P) applications and shows reactivity with mouse, Non-human primate, Rat, Canine, Equine, Human, Ovine, and Porcine samples. Staining of formalin-fixed tissues requires boiling in 10mM citrate buffer pH 6.0 for 10-20 minutes followed by cooling at RT for 20 minutes.
The PA5-16464 immunogen is a synthetic peptide from human calcitonin.
Calcitonin is a 32 amino acid peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alpha CGRP; Alpha type CGRP; Alpha-type CGRP; Calcitonin; calcitonin 1; calcitonin gene related peptide 1; calcitonin gene related peptide I; Calcitonin gene-related peptide; Calcitonin gene-related peptide 1; Calcitonin gene-related peptide I; calcitonin-related polypeptide alpha; calcitonin/calcitonin-related polypeptide, alpha; CGRP-I; katacalcin; katacalcin (KC); prepro-alpha-calcitonin gene-related peptide; procalcitonin
基因别名: CA; Cal1; CAL6; CALC; CALC1; CALCA; Calcitonin; CCALCI; CGRP; CGRP-1; CGRP-I; CGRP1; CGRPI; CT; Ctn; KC; PCT; RATCAL6
UniProt ID: (Dog) Q9MYV1, (Horse) Q9N0T2, (Human) P06881, (Rat) P01256, (Mouse) Q99JA0
Entrez Gene ID: (Dog) 403946, (Horse) 100033906, (Human) 796, (Sheep) 100294596, (Rat) 24241, (Mouse) 12310
分子生物学功能: peptide hormone