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This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
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MA5-12800 targets Galphai1 G-Protein in WB applications and shows reactivity with Bovine, Guinea Pig, Human, mouse, and Rat samples.
The MA5-12800 immunogen is partially purified rat brain Galphai1 protein.
Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain; and transducin-1 and transducin-2, proteins involved in phototransduction in retinal rods and cones, respectively.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Adenylate cyclase-inhibiting G alpha protein; Gi1 protein alpha subunit; Gi1 protein alpha-subunit; guanine nucleotide binding protein (G protein), alpha inhibiting 1; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1; guanine nucleotide binding protein, alpha inhibiting 1; Guanine nucleotide-binding protein G(i) subunit alpha-1; guanine nucleotide-binding protein G(i), alpha-1 subunit; p-alpha-h subunit; unnamed protein product
基因别名: AU046200; BPGTPB; Gi; Gialpha1; Gnai-1; GNAI1
UniProt ID: (Bovine) P63097, (Human) P63096, (Guinea pig) P38401, (Rat) P10824, (Mouse) B2RSH2
Entrez Gene ID: (Bovine) 281790, (Human) 2770, (Guinea pig) 100135528, (Rat) 25686, (Mouse) 14677
分子生物学功能: heterotrimeric G-protein