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Keep as concentrated solution.
Positive Control: SH-SY5Y, SH-SY5Y membrane fraction extract, unboiled SH-SY5Y, unboiled SH-SY5Y membrane fraction extract, mouse liver.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
HTR2B is a g-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. HTR2B also plays a role in perception of pain, regulation of behavior. It is required to normal proliferation of embryonic cardiac myocytes and normal heart development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 5-HT 2B receptor; 5-HT-2B; 5-HT-2F; 5-HT2b receptor; 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled; 5-hydroxytryptamine 2B receptor; 5-hydroxytryptamine receptor 2B; 5-hydroxytryptamine receptor 2B variant b; 5HT2B Receptor; NP75 protein; Serotonin receptor 2B
基因别名: 5-HT(2B); 5-HT-2B; 5-HT2B; AJ012488; AV377389; HTR2B
UniProt ID: (Human) Q53TI1, (Mouse) Q02152
Entrez Gene ID: (Human) 3357, (Mouse) 15559
分子生物学功能: G-protein coupled receptor