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Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (95%), Rat (95%), Chicken (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Myeloid tumor related gene (MTGR1) is found deleted in acute myeloid leukemia. Overexpression of MTGR1 can stimulate AML1-MTG8 to induce GCSF- dependent proliferation of L-G cells and to interfere with AML1- dependent transcription. AML1/MTG8 functions as a complex with MTGR1 and that the complex might be important in promoting leukemogenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: core-binding factor, runt domain, alpha subunit 2; translocated to, 2; DKFZp313F2116; ETO homolog on chromosome 20; ETO homologous on chromosome 20; MTG8-like protein; MTG8-related protein 1; myeloid translocation gene-related protein 1; Myeloid translocation-related protein 1; p85; Protein CBFA2T2; RP5-1137F22.1; ZMYND3 CBFA2T2
基因别名: CBFA2T2; EHT; MTGR1; p85; ZMYND3
UniProt ID: (Human) O43439
Entrez Gene ID: (Human) 9139