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Invitrogen
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This target displays homology in the following species: Mouse: 100%
Spermatogenic leucine zipper protein 1 is a member of the basic helix-loop-helix (bHLH) family of transcription factors which is expressed specifically in the testis and epididymis. Studies show that SPZ1 acts downstream of mitogen-activated protein kinase (MAPK), an extracellular signal-regulated kinase 1/2 to up-regulate cell proliferation and tumorigenesis. Also, through an interaction with proliferating cell nuclear antigen (PCNA) promoter, SPZ1 induced cell proliferation concomitant with an increase in PCNA gene expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BHLH-Zip transcription factor SPZ1; Spermatogenic leucine zipper protein 1; Spermatogenic Zip 1
基因别名: 1700027M20Rik; AI429130; Spz1
UniProt ID: (Mouse) Q99MY0
Entrez Gene ID: (Mouse) 79401