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产品信息
ASC0944
应用
建议稀释比
已发表文章
产品规格
种属反应
Pig
已发表种属
Pig
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
A155B16F2
抗原
Recombinant swine IL-4.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.5
内含物
0.5mg/mL sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2536424
产品详细信息
This product is recommended as a capture antibody in Sandwich ELISA applications.
This clone can also be referred to as clone number A155B 16F2 1A9.
靶标信息
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: B-cell stimulatory factor 1; BSF-1; cytokine; H-IL-4; IL-4; ILN; Interleukin; Interleukin-4; Interleukin4; Lymphocyte stimulatory factor 1; M-IL-4; MGC79402
基因别名: IL4
UniProt ID: (Pig) Q04745
Entrez Gene ID: (Pig) 397225
positive regulation of protein phosphorylation
positive regulation of gene expression
positive regulation of macroautophagy
B cell activation
negative regulation of transcription, DNA-templated
positive regulation of JAK-STAT cascade
regulation of protein export from nucleus
positive regulation of establishment of endothelial barrier
negative regulation of complement-dependent cytotoxicity
negative regulation of endothelial cell apoptotic process
