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This gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ITBA4 protein; NF-kappa-B-repressing factor; NFkB-repressing factor; Protein ITBA4; transcription factor NRF
基因别名: ITBA4; NKRF; NRF
UniProt ID: (Human) O15226
Entrez Gene ID: (Human) 55922
分子生物学功能: DNA-binding transcription factor