Lipofectamine™ RNAiMAX Transfection Reagent
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Lipofectamine™ RNAiMAX Transfection Reagent
Lipofectamine™ RNAiMAX Transfection Reagent
Lipofectamine™ RNAiMAX Transfection Reagent
Invitrogen™

Lipofectamine™ RNAiMAX Transfection Reagent

Green features
Achieve effective RNAi transfection with Lipofectamine RNAiMAX Transfection Reagent across a wide range of cell types. This lipid-based transfection reagent is optimized for siRNA and miRNA transfection, offering high delivery efficiency and low cellular toxicity, enabling effective gene silencing.
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Catalog NumberQuantity
137780750.75 mL
137781501.5 mL
137781000.1 mL
137780300.3 mL
1377850015 mL
Catalog number 13778075
Price (CNY)
6,973.00
Each
Add to cart
Quantity:
0.75 mL
Price (CNY)
6,973.00
Each
Add to cart

Lipofectamine RNAiMAX reagent is a leading transfection reagent designed specifically for RNA interference applications. It efficiently delivers siRNA and miRNA into a wide variety of cell types, ensuring high transfection efficiency and effective gene knockdown. The proprietary cationic lipid formulation minimizes cytotoxicity, making it suitable for sensitive cells and long-term studies. Lipofectamine RNAiMAX reagent is optimized for consistent performance, providing researchers with reliable results in gene silencing experiments. Its ease of use and compatibility with high-throughput screening make it an essential tool for basic biology research and functional genomics.

Features of Lipofectamine RNAiMAX Transfection Reagent

  • Optimized for RNAi—Specifically formulated for RNA interference applications, maximizing siRNA and miRNA transfection and gene silencing.
  • Superior siRNA transfection efficiency—requires lower siRNA concentrations for effective gene knockdown
  • miRNA reagent compatible—provides superior transfection efficiencies for miRNA mimics and inhibitors
  • Minimal cytotoxicity—flexible 10-fold concentration range of the siRNA transfection reagent with low cellular impact
  • Broad cell type compatibility—versatile use in a wide range of cell lines, including hard-to-transfect cells
  • Simple and rapid protocol—easy-to-follow steps that save time and effort in the lab for consistent and reproducible results

High knockdown in a wide range of cells

Lipofectamine RNAiMAX Transfection Reagent is an effective siRNA transfection reagent suitable for a wide range of cell types, including primary cells (see figure). It achieves high-efficiency siRNA transfection, leading to significant gene knockdown necessary for convincing gene silencing results.

Simple, high-throughput-ready transfections

Mix Lipofectamine RNAiMAX Transfection Reagent with siRNA, add to your cells, incubate, and measure gene knockdown. Its simplicity and speed, combined with high transfection efficiency, make it ideal for high-throughput siRNA transfection workflows. Whether it's a forward or reverse transfection protocol, siRNA transfection conditions can be easily optimized for automated or robotic systems.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
For Use With (Application)Transfection
Green FeaturesSustainable packaging
High-throughput CompatibilityHigh-throughput Compatible
Product LineLipofectamine™
Product TypeTransfection Reagent
Quantity0.75 mL
Serum CompatibleYes
Shipping ConditionApproved for shipment at Room Temperature or on Wet Ice
Cell TypeEstablished Cell Lines, Stem Cells, Primary Cells, Hard-to-Transfect Cells
Format6-well Plate, 12-well Plate, 24-well Plate, 48-well Plate, 96-well Plate, Flasks
Sample TypeSynthetic siRNA, siRNA, miRNA
Transfection TechniqueLipid-based Transfection
Unit SizeEach
Contents & Storage
Contains one vial (0.75 ml) Lipofectamine™ RNAiMAX Transfection Reagent. Store at 2–8°C. Do not freeze.

Frequently asked questions (FAQs)

I'm seeing cell death after transfection using Lipofectamine RNAiMAX Reagent. What should I do?

Remove antibiotics from the medium during transfection, as this can cause stress leading to cell death. Try adjusting both lipid and siRNA quantities. Use cells with lower passage number for better viability. Consider assaying for microbes such as Mycoplasma that are not detected easily in cell culture.

Find additional tips, troubleshooting help, and resources within our Transfection Support Center.

I accidentally kept my Lipofectamine RNAiMAX Reagent at room temperature. Can I still use it?

Yes, all of our lipid transfection reagents are stable at room temperature for months.

Find additional tips, troubleshooting help, and resources within our Transfection Support Center.

I accidentally froze my Lipofectamine RNAiMAX Reagent. Can I still use it?

Freezing can alter the integrity and composition of the lipid particles. The performance of the reagent may be affected and it may only work for the first week or so. It is safer to use a new vial.

Find additional tips, troubleshooting help, and resources within our Transfection Support Center.

I accidentally left my lipid reagent at room temperature. Can I still use it?

Yes, all of our lipid transfection reagents are stable at room temperature for months.

Find additional tips, troubleshooting help, and resources within our Lipid-Based Transfection Support Center.

What positive transfection control can I use with Lipofectamine RNAiMAX?

BLOCK-iT Alexa Fluor Red Fluorescent Control (Cat. No. 14750100) can be used as an indicator of transfection efficiency of siRNA. This dye can be detected using standard filter sets designed for Alexa Fluor 555, Cy3, DsRed, Texas Red, or Rhodamine Red fluorophores.

Find additional tips, troubleshooting help, and resources within our Transfection Support Center.