2'-OMe-Ac-C Phosphoramidite, standard grade, 20-400 finish bottle
2'-OMe-Ac-C Phosphoramidite, standard grade, 20-400 finish bottle
Thermo Scientific™

2'-OMe-Ac-C Phosphoramidite, standard grade, 20-400 finish bottle

2'-OMe-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotideRead more
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Catalog NumberQuantity
27-1823-101 g
Catalog number 27-1823-10
Price (CNY)
203.00
Each
Add to cart
Quantity:
1 g
Price (CNY)
203.00
Each
Add to cart

2'-OMe-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

Features:
• HPLC purity—≥98.0%; Sum of PIII impurities (140-152ppm) ≤0.5%

For Research Use Only. Not for use in diagnostic procedures.
Specifications
31P NMR Purity≥98.0%
CAS199593-09-4
Chemical Name or Material5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-O-methyl-cytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
DescriptionBase: C
Base Protection: Ac
For Use With (Application)Oligonucleotide synthesis
For Use With (Equipment)Expedite Synthesizers
FormPowder
FormatAmber bottle (20-400 finish neck style)
GradeStandard
Molecular FormulaC42H52N5O9P
Molecular Weight (g/mol)801.86 g/mol
Nucleic Acid TypeRNA
Nucleoside TypeCytidine (C)
Product Type2in-OMe-Ac-C CEP
Purity≥98% (HPLC)
Quantity1 g
Reagent Features2in-OMe modified, Fast deprotection
Reagent TypePhosphoramidite
Shipping ConditionRoom Temperature
Unit SizeEach
Contents & Storage
Store in freezer (at or below -20°C).