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KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
7420700M05Rik; AA420409; AU043468; C85123; D4Ertd561e; FLJ40160; germ cell specific zinc finger protein; germ cell-specific zinc finger protein; Gzf; KLF17; Krueppel-like factor 17; Kruppel like factor 17; Kruppel-like factor 17; novel zinc-finger protein; Zfp393; Zinc finger protein 393; ZLF393; ZNF393
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