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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: TVPSTEAQAV LPSMAQMLPP QDAHDLGMPP AESQSLLVLG SQDSLVSQPD SQEGPFLPEQ PGPAPQTVEK NSRPQEGTG
Highest antigen sequence identity to the following orthologs: Mouse - 42%, Rat - 46%.
KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ40160; Krueppel-like factor 17; Zinc finger protein 393; ZLF393
Gene Aliases: KLF17; ZNF393
Entrez Gene ID: (Human) 128209
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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