Invitrogen

KLF17 Polyclonal Antibody

Name: KLF17 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-31774

查看其他12个KLF17抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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KLF17 Antibody (PA5-31774) in WB

Western Blot using KLF17 Polyclonal Antibody (Product # PA5-31774). Sample (30 µg of whole cell lysate). Lane A: MCF-7. 10% SDS PAGE. KLF17 Polyclonal Antibody (Product # PA5-31774) diluted at 1:500.

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产品信息

PA5-31774

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein encompassing a sequence within the center region of human KLF17. The exact sequence is proprietary.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 1% BSA, 20% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2549247

产品详细信息

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7.

Predicted reactivity: Human (98%), Chimpanzee (97%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。