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This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Recommended positive controls: H1299, HeLaS3, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (100%), Dog (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ARHGAP 7; Deleted in liver cancer 1 protein; deleted in liver cancer 1 variant 2; deleted in liver cancer variant 4; DLC 1; DLC-1; FLJ21120; HP protein; p122 RhoGAP; Rho GTPase-activating protein 7; Rho-GTPase-activating protein 7; Rho-type GTPase-activating protein 7; StAR-related lipid; StAR-related lipid transfer (START) domain containing 12; StAR-related lipid transfer protein 12; STARD 12; StARD12; START domain-containing protein 12; transfer protein 12
基因别名: ARHGAP7; DLC1; HP; KIAA1723; p122-RhoGAP; STARD12
UniProt ID: (Human) Q96QB1
Entrez Gene ID: (Human) 10395
分子生物学功能: G-protein modulator protein-binding activity modulator GTPase-activating protein