Antibodies that detect PPAPDC3 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunoprecipitation and Immunocytochemistry. These antibodies target PPAPDC3 in Human, Rat and Mouse samples. Our PPAPDC3 polyclonal antibodies are developed in Rabbit. Find the PPAPDC3 antibody that fits your needs. Choose from 1 of 3 PPAPDC3 antibodies, which have been validated in experiments with 1 publication and 7 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more
PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.