Striatin is found in all mammalian cells assayed and may be involved in vesicular transport, dendrite growth, and cellular signaling. It binds Protein phosphatase 2A (PP2A) A and C subunits and calmodulin and appears to modulate PP2A activity. It also binds the human homolog of the yeast protein, Mob1, which has been implicated in mitotic progression in yeast. It is a member of a family of proteins that also includes SG2NA and Zinedin. This antibody does not cross-react with SG2NA.
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