Antibodies that detect TECTA can be used in several scientific applications, including Western Blot and Immunohistochemistry (Paraffin). This Rabbit polyclonal antibody targets TECTA in Rat, Mouse and Human samples, and has been validated in experiments with 4 images featured in our data gallery.
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Alpha-tectorin is a protein that in humans is encoded by the TECTA gene. The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual non-syndromic deafness.