Antibodies that detect AXIN2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target AXIN2 in Human, Mouse and Rat samples. Our AXIN2 polyclonal, recombinant monoclonal and...Antibodies that detect AXIN2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target AXIN2 in Human, Mouse and Rat samples. Our AXIN2 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in...Antibodies that detect AXIN2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target AXIN2 in Human, Mouse and Rat samples. Our AXIN2 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockout, Relative expression and Knockdown to confirm specificity to AXIN2. Find the AXIN2 antibody that fits your needs. Choose from 1 of 20 AXIN2 antibodies, which have been validated in experiments with 41 publications and 55 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications....
Antibodies that detect AXIN2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target AXIN2 in Human, Mouse and Rat samples. Our AXIN2 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockout, Relative expression and Knockdown to confirm specificity to AXIN2. Find the AXIN2 antibody that fits your needs. Choose from 1 of 20 AXIN2 antibodies, which have been validated in experiments with 41 publications and 55 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.
同义词
Axi1; axil; axin 2; Axin like protein; axin2; axin-2; Axin-like protein; Axis inhibition protein 2; conductin; DKFZp781B0869; MGC10366; MGC126582; ODCRCS
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party
scientific content. Neither the content nor the BenchSci technology and processes for
selection have been evaluated by us; we are providing them as-is and without warranty of any kind,
including for use or application of the Thermo Fisher Scientific products presented.