Antibodies that detect CD16b can be used in several scientific applications, including ELISA, Western Blot, Functional Assay, Immunocytochemistry and Flow Cytometry. These antibodies target CD16b in Human, Rat and Porcine samples. Our CD16b polyclonal, recombinant monoclonal and monoclonal...Antibodies that detect CD16b can be used in several scientific applications, including ELISA, Western Blot, Functional Assay, Immunocytochemistry and Flow Cytometry. These antibodies target CD16b in Human, Rat and Porcine samples. Our CD16b polyclonal, recombinant monoclonal and monoclonal antibodies are developed in...Antibodies that detect CD16b can be used in several scientific applications, including ELISA, Western Blot, Functional Assay, Immunocytochemistry and Flow Cytometry. These antibodies target CD16b in Human, Rat and Porcine samples. Our CD16b polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Alpaca and Mouse. Find the CD16b antibody that fits your needs. Choose from 1 of 10 CD16b antibodies, which have been validated in experiments with 5 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen...
Antibodies that detect CD16b can be used in several scientific applications, including ELISA, Western Blot, Functional Assay, Immunocytochemistry and Flow Cytometry. These antibodies target CD16b in Human, Rat and Porcine samples. Our CD16b polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Alpaca and Mouse. Find the CD16b antibody that fits your needs. Choose from 1 of 10 CD16b antibodies, which have been validated in experiments with 5 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FCGR3A is associated, with FcepsilonRI-beta subunit. Besides IgG, FCGR3A can be triggered also by oligomeric IgE. FCGR3B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a pro-adhesive phenotype. Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.
同义词
CD16; CD16B; Fc fragment of IgG receptor IIIb; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor IIIb; FCG3; Fc-gamma receptor IIIb (CD 16); Fc-gamma RIII; fc-gamma RIIIb; Fc-gamma RIII-beta; FCGR3; FCGR3B; FcR-10; FCRIII; FCRIIIb; IGFR3; IgG Fc receptor III-1; low affinity immunoglobulin gamma Fc region receptor III-B
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