cGAS Antibodies

Antibodies that detect cGAS can be used in several scientific applications, including Western Blot, ELISA, Immunoprecipitation, Immunocytochemistry and Immunohistochemistry. These antibodies target cGAS in Human, Mouse, Rat and Porcine samples. Our cGAS polyclonal, recombinant... Antibodies that detect cGAS can be used in several scientific applications, including Western Blot, ELISA, Immunoprecipitation, Immunocytochemistry and Immunohistochemistry. These antibodies target cGAS in Human, Mouse, Rat and Porcine samples. Our cGAS polyclonal, recombinant monoclonal and monoclonal antibodies are... Antibodies that detect cGAS can be used in several scientific applications, including Western Blot, ELISA, Immunoprecipitation, Immunocytochemistry and Immunohistochemistry. These antibodies target cGAS in Human, Mouse, Rat and Porcine samples. Our cGAS polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment, Knockdown, Knockout and Relative expression to confirm specificity to cGAS. Find the cGAS antibody that fits your needs. Choose from 1 of 31 cGAS antibodies, which have been validated in experiments with 67 publications and 81 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP,... Antibodies that detect cGAS can be used in several scientific applications, including Western Blot, ELISA, Immunoprecipitation, Immunocytochemistry and Immunohistochemistry. These antibodies target cGAS in Human, Mouse, Rat and Porcine samples. Our cGAS polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment, Knockdown, Knockout and Relative expression to confirm specificity to cGAS. Find the cGAS antibody that fits your needs. Choose from 1 of 31 cGAS antibodies, which have been validated in experiments with 67 publications and 81 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

cGAS (Cyclic GMP-AMP synthase) is a nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP and plays a key role in innate immunity. Catalysis involves both the formation of 2', 5' phosphodiester linkage at the GpA step and the formation of 3', 5' phosphodiester linkage at the ApG step. This produces c[G(2',5')pA(3'5')p] responses. cGAS also binds cytosolic DNA directly, leading to the activation and synthesis of cGAMP. Then, a second messenger binds to and activates TMEM173/STING thereby triggering type-I interferon production. cGAS is also involved in innate immune sensorship of infection, detection of DNA from bacteria, response to cellular stress, DNA damage, and regulation of cellular senescence.

同义词

C6orf150; h-cGAS; MB21D1

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cGAS Antibodies

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