Antibodies that detect DOK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target DOK1 in Human, Rat and Mouse samples. Our DOK1 polyclonal and recombinant monoclonal...Antibodies that detect DOK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target DOK1 in Human, Rat and Mouse samples. Our DOK1 polyclonal and recombinant monoclonal antibodies are developed in Rabbit and...Antibodies that detect DOK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target DOK1 in Human, Rat and Mouse samples. Our DOK1 polyclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. Find the DOK1 antibody that fits your needs. Choose from 1 of 22 DOK1 antibodies, which have been validated in experiments with 1 publication and 32 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen...
Antibodies that detect DOK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target DOK1 in Human, Rat and Mouse samples. Our DOK1 polyclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. Find the DOK1 antibody that fits your needs. Choose from 1 of 22 DOK1 antibodies, which have been validated in experiments with 1 publication and 32 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
DOK1 (P62dok, Docking protein 1) is believed to be a mainly cytoplasmic adaptor protein which down-regulates mitogen-activated protein kinase activation, inhibits cell proliferation and transformation, and promotes cell spreading and cell migration. DOK1 is a major substrate for many tyrosine kinases including c-kit, v-abl, vFPS, EGF, and PDGF. Upon phosphorylation by kinases, DOK1 forms a complex with ras GTPase-activating protein. Phosphorylation on tyrosine residues by the insulin receptor kinase results in the negative regulation of the insulin signaling pathway. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs.
同义词
AW557123; Docking protein 1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); Dok; DOK 1; DOK1; Dok-1; Downstream of tyrosine kinase 1; downstream of tyrosine kinase-1; MGC117395; MGC138860; p240; p62 dok; p62(dok); p62DOK; pp62; TLP1; TP1; TROVE domain family; TROVE1; VAULT2
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