Antibodies that detect DUX4 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target DUX4 in Human, Mouse and Rat samples. Our DUX4 monoclonal and polyclonal...Antibodies that detect DUX4 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target DUX4 in Human, Mouse and Rat samples. Our DUX4 monoclonal and polyclonal antibodies are developed in Mouse and Rabbit. Find the...Antibodies that detect DUX4 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target DUX4 in Human, Mouse and Rat samples. Our DUX4 monoclonal and polyclonal antibodies are developed in Mouse and Rabbit. Find the DUX4 antibody that fits your needs. Choose from 1 of 14 DUX4 antibodies, which have been validated in experiments with 5 publications and 34 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the...
Antibodies that detect DUX4 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target DUX4 in Human, Mouse and Rat samples. Our DUX4 monoclonal and polyclonal antibodies are developed in Mouse and Rabbit. Find the DUX4 antibody that fits your needs. Choose from 1 of 14 DUX4 antibodies, which have been validated in experiments with 5 publications and 34 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
DUX4 (also known as Double homeobox 4) is the leading candidate causative gene for facioscapulohumeral dystrophy (FSHD), a degenerative skeletal muscle disease and one of the most common muscular dystrophies. FSHD is caused by the deletion of a subset of D4Z4 macrosatellite repeats on chromosome 4. Each repeat contains a retrogene encoding the double-homeobox factor DUX4. DUX4 expression is epigenetically suppressed in differentiated tissues and the residual DUX4 transcripts are spliced to remove the carboxyterminal domain that has been associated with cell toxicity. In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle, and possibly other differentiated tissues, and results in a small percentage of cells expressing relatively abundant amounts of the full-length DUX4 mRNA and protein.
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party
scientific content. Neither the content nor the BenchSci technology and processes for
selection have been evaluated by us; we are providing them as-is and without warranty of any kind,
including for use or application of the Thermo Fisher Scientific products presented.